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Action/Kinetics:
Both beta-1- and beta-2-adrenergic receptor agonist. May act by decreasing the formation of aqueous humor.
Onset: <60 min.
Peak effect: 2-6 hr.
Duration: 24 hr.
Uses:
To decrease intraocular pressure in chronic open-angle glaucoma or ocular hypertension.
Special Concerns:
Safety and effectiveness have not been determined in children. Significant absorption in geriatric clients may result in myocardial depression. Also, use with caution in angle-closure glaucoma (use with a miotic), in clients with muscle weaknesses, and in those with decreased pulmonary function.
Additional Side Effects:
Ophthalmic: Stinging and burning (transient), decreased corneal sensitivity, blepharoconjunctivitis.
Dermatologic: Urticaria, pruritus.
How Supplied:
Ophthalmic Solution: 0.25%, 0.5%
Dosage
?Ophthalmic Solution (0.25%, 0.5%)
Adults, usual: 1-2 gtt of 0.25% solution in affected eye(s) b.i.d. or 1-2 gtt of 00.5% solution in affected eye(s) once a day (use b.i.d. in more severe or uncontrolled glaucoma).
