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Beclomethasone dipropionate
Beclomethasone dipropionate (Beclovent, Vanceril)
Beclomethasone dipropionate
(be-kloh-
METH-ah-zohn)
Pregnancy Category: C
Aerosol Inhaler: Alti-Beclomethasone Dipropionate
Beclodisk Diskhaler
Becloforte Inhaler
Beclovent
Beclovent Rotacaps or Rotahaler
Vanceril
Vanceril Double Strength
(Rx)
Intranasal: Beclodisk for Oral Inhalation
Beconase AQ Nasal
Beconase Inhalation
Gen-Beclo Aq.
Vancenase AQ
Vancenase Nasal Inhaler
Vancenase Pockethaler
(Rx)
Topical: Propaderm
Classification:
Glucocorticoid
See Also:
See also
Corticosteroids
[.
]
Action/Kinetics:
t
1/2, after intranasal: 0.5 hr. Rapidly inactivated, thereby resulting in few systemic effects.
Uses:
Relief of symptoms of seasonal or perennial rhinitis in clients not responsive to more conventional therapy and to prevent recurrence of nasal polyps following surgical removal. Spray formulations: to treat allergic or nonallergic (vasomotor) rhinitis.
Inhalation therapy for chronic asthma. Vanceril Aerosol is only for those who require chronic steroid treatment for bronchial asthma. Beclovent and Vanceril Double Strength are for maintenance of prophylactic therapy. In glucocorticoid-dependent clients, inhaled beclomethasone often permits a decrease in the dosage of systemic steroids. Withdrawal of systemic corticosteroids must be done gradually.
Contraindications:
Status asthmaticus, acute episodes of asthma, hypersensitivity to drug or aerosol ingredients.
Special Concerns:
Safe use during lactation and in children under 6 years of age not established.
Side Effects:
Intranasal: Headache, pharyngitis, coughing, epistaxis, nasal burning, pain, conjunctivitis, myalgia, tinnitus. Rarely, ulceration of the nasal mucosa and nasal septum perforation.
How Supplied:
Aerosol: 42 mcg/inh, 84 mcg/inh;
Nasal Spray: 0.042%, 0.084%
Dosage
?Metered Dose Inhaler
Asthma.
Beclovent.
Adults and children over 12 years old: 2 inhalations (total of 84 mcg beclomethasone) t.i.d.-q.i.d. In some clients, 4 inhalations (168 mcg) b.i.d. have been effective. Do not exceed 20 inhalations (840 mcg) daily.
Pediatric, 6-12 years: 1-2 inhalations (42-84 mcg) t.i.d.-q.i.d. In some, 4 inhalations (168 mcg) b.i.d. have been effective. Do not to exceed 10 inhalations (420 mcg) daily. Dosage has not been determined in children less than 6 years of age.
Vanceril.
Adults: 2 inhalations (total of 84 mcg) t.i.d.-q.i.d. In some clients, 4 inhalations (168 mcg) has been effective. In those with severe asthma, start with 12-16 inhalations/day and adjust dose downward as determined by client response. Do not exceed 20 inhalations (840 mcg) daily.
Children, 6-12 years: 1 or 2 inhalations (42-84 mcg) t.i.d.-q.i.d., not to exceed 10 inhalations (420 mcg) daily. Dosage has not been determined in children less than 6 years of age.
Vanceril Double Strength.
Adults: 2 inhalations (168 mcg) b.i.d. In clients with severe asthma, start with 6-8 inhalations/day and adjust dose downward depending on client respoinse. Do not exceed 10 inhalations (840 mcg) daily.
Children, 6-12 years: 2 inhalations (168 mcg) b.i.d. Do not exceed 5 inhalations (420 mcg) daily. Dosage has not been determined in children less than 6 years of age.
In clients also receiving systemic glucocorticosteroids, beclomethasone should be started when client's condition is relatively stable.
?Nasal Aerosol or Spray
Allergic or nonallergic rhinitis, Prophylaxis of nasal polyps.
Adults and children over 12 years.
Beconase, Vancenase: 1 inhalation (42 mcg) in each nostril b.i.d.-q.i.d. (i.e., total daily dose: 168-336 mcg). Clients can be maintained on a maximum dose of 1 inhalation in each nostril t.i.d. (252 mcg/day).
Beconase AQ: 1 or 2 inhalations (42-84 mcg) in each nostril b.i.d. (168-336 mcg/day).
Vancenase Pockethaler: 1 inhalation (42 mcg) in each nostril b.i.d.-q.i.d. (total dose of 168-336 mcg/day).
Maintenance: 1 inhalation in each nostril t.i.d. (252 mcg/day).
Children 6-12 years:
Beconase, Vancenase: 1 inhalation in each nostril t.i.d. (252 mcg/day). Do not use in children less than 6 years of age.
Beconase AQ: Initially, 1 inhalation in each nostril b.i.d. Those not responding to 168 mcg or those with more severe symptoms may use 2 inhalations in each nostril b.i.d. (total of 336 mcg). Do not use in children less than 6 years of age.
Vancenase Pockethaler: 1 inhalation in each nostril t.i.d. (252 mcg/day). Do not use in children less than 6 years of age.
Adults and children 6 years of age and older:
Vancenase AQ: 1 or 2 inhalations in each nostril once daily (total dose of 168-336 mcg/day) at regular intervals. Not recommended for children less than 6 years of age.
Note: For nasal use, symptoms usually improve in a few days but relief may not be seen in some clients for up to 2 weeks. Do not continue therapy beyond 3 weeks if symptoms do not improve. For nasal polyps treatment may be required for several weeks or more before a beneficial result can be assessed. Recurrence of nasal polyps can occur after stopping treatment. |