Questions | Reviews
I would like to know what is the exact dosage of azithromycin for clamydia. i've been given 4 tablets, 250 mg of it . Am i suppose to take it as a single dose?
by juliza in newyork city, 12/26/2006
Hello, I have a question that I think could tie into this new antibiotic that was prescribed by my daughter's pediatrition yesterday. I gave her the reccomended dosage of the Azithromycin starting last night at 8pm. Everything seems to be going ok...
by Steve in Michigan, 01/26/2007
i have a 6 year old patient who can't take meds by mouth and needs empiric therapy for pneumonia with azithromycin. He is in ICU . what dose should i give him?
by karimah in USA, 09/26/2006
I have diabetes for which I take a daily dosage of 2mg Glimepiride; doctor prescribed Azithromycin for bronchial problem. Have taken first double dosage at 9:00 P.M. last evening, and single dosage at 8:00 A.M. this morning (3 more single doses to fol...
by F.G. in Norfolk, Virginia, 07/29/2006
Classification: Antibiotic, macrolide
See Also: Anti-Infectives
Action/Kinetics: A macrolide antibiotic derived from erythromycin. The drug acts by binding to the P site of the 50S ribosomal subunit and may inhibit RNA-dependent protein synthesis by stimulating the dissociation of peptidyl t-RNA from ribosomes. Rapidly absorbed and distributed widely throughout the body. Food increases the absorption of azithromycin. Time to reach maximum concentration: 2.2 hr. t 1/2, terminal: 68 hr. A loading dose will achieve steady-state levels more quickly. Mainly excreted unchanged through the bile with a small amount being excreted through the kidneys.
Adults: Acute bacterial exacerbations of COPD due to
Hemophilus influenzae, Moraxella catarrhalis or
Streptococcus pneumoniae. Required initial IV therapy in community-acquired pneumonia due to
Chlamydia pneumoniae, Mycoplasma pneumoniae, H. influenzae, M. catarrhalis, Legionella pneumophila, and
Staphylococcus aureus. Those who can take PO therapy in community-acquired pneumonia due to
C. pneumoniae, M. pneumoniae, S. pneumoniae, or H. influenzae. PO for genital ulcer disease in men due to
Haemophilus ducreyi. Initial IV therapy in pelvic inflammatory disease due to
Chlamydia trachomatis, Neisseria gonorrhoeae or
Mycoplasma hominis. As an alternative to first-line therapy to treat streptococcal pharyngitis or tonsillitis due to
Streptococcus pyogenes. PO for uncomplicated skin and skin structure infections due to
S. aureus, Staphyloccus pyogenes or
Streptococcus agalactiae. Abscesses usually require surgical drainage. PO for urethritis and cervicitis due to
C. trachomatis or
Investigational: Uncomplicated gonococcal pharyngitis of the cervix, urethra, and rectum caused by N. gonorrhoeae. Gonococcal phayrngitis due to N. gonorrhoeae. Chlamydial infections due to C. trachomatis.
Contraindications: Hypersensitivity to azithromycin, any macrolide antibiotic, or erythromycin. In clients who are not eligible for outpatient PO therapy (e.g., known or suspected bacteremia, immunodeficiency, functional asplenia, nosocomially acquired infections, geriatric or debilitated clients). Use with astemizole, cisapride, or pimozide.
Special Concerns: Use with caution in clients with impaired hepatic or renal function and during lactation. Safety and efficacy for acute otitis media have not been determined in children less than 6 months of age or for pharyngitis/tonsillitis in children less than 2 years of age.
Side Effects: GI: N&V, diarrhea, loose stools, abdominal pain, dyspepsia, anorexia, gastritis, flatulence, melena, mucositis, oral moniliasis, taste perversion, cholestatic jaundice, pseudomembranous colitis. In children, gastritis, constipation, and anorexia have also been noted. CNS: Dizziness, headache, somnolence, fatigue, vertigo. In children, hyperkinesia, agitation, nervousness, insomnia, fever, and malaise have also been noted. CV: Chest pain, palpitations, ventricular arrhythmias (including ventricular tachycardia and torsades de pointes in clients with prolonged QT intervals observed with other macrolides). GU: Monilia, nephritis, vaginitis. Allergic: Angioedema, photosensitivity, rash, anaphylaxis. Hematologic: Leukopenia, neutropenia, decreased platelet count. Miscellaneous: Superinfection, bronchospasm, local IV site reactions. In children, pruritus, urticaria, conjunctivitis, and chest pain have been noted.
Laboratory Test Alterations: Serum CPK, potassium, ALT, GGT, AST, serum alkaline phosphatase, bilirubin, BUN, creatinine, blood glucose, LDH, and phosphate.
Drug Interactions for
Powder for Injection: 500 mg;
Powder for Oral Suspension: 100 mg/5mL, 200 mg/5mL, 1 gm/packet;
Tablet: 250 mg, 600 mg
How Supplied: Powder for Injection: 500 mg; Powder for Oral Suspension: 100 mg/5mL, 200 mg/5mL, 1 gm/packet; Tablet: 250 mg, 600 mg