Aurothioglucose Suspension


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Aurothioglucose
Aurothioglucose (Solganol)
Aurothioglucose
(or-oh-thigh-oh- GLOO-kohz)
Pregnancy Category: C Solganol (Rx)

Classification: Antiarthritic

See Also: For additional information regarding aurothioglucose, see Gold Sodium Thiomalate .

Action/Kinetics: The gold content of aurothioglucose is 50%. Time to peak effect: 4-6 hr. Mean steady-state plasma levels: 1-6 mc/mL. Is 95%-99% protein bound. t 1/2, after 11th dose: Up to 168 days. Seventy percent is excreted in the urine and 30% is excreted through the urine.

Side Effects: GI: N&V, anorexia, abdominal cramps, metallic taste, gastritis, ulcerative enterocolitis colitis. Dermatologic: Dermatitis (papular, vesicular, exfoliative), rash, urticaria, angioedema, chrysiasis. Renal: Nephrotic syndrome, glomerulonephritis with proteinuria and hematuria, acute renal failure secondary to acute tubular necrosis, acute nephritis, degeneration of proximal tubular epithelium. Hematologic: Granulocytopenia, panmyelopathy, hemorrhagic diathesis. Respiratory: Inflammation of upper respiratory tract, pharyngitis, tracheitis, bold bronchitis, interstitial pneumonitis, fibrosis. CNS: Confusion, hallucinations, seizures. Mucous membranes: Stomatitis, diffuse glossitis, gingivitis. Reactions of the nitroid type: Anaphylactoid symptoms, flushing, fainting, dizziness, sweating, N&V, malaise, headache, weakness. Ophthalmologic: Iritis, corneal ulcers, gold deposits in ocular tissues. Miscellaneous: Vaginitis.

Overdose Mangement: Treatment: Discontinue and give dimercaprol. Provide supportive therapy for renal and hematologic symptoms. In acute overdose, induce emesis or gastric lavage immediately.

How Supplied: Injection: 50 mg/mL

Dosage
•IM Only Rheumatoid arthritis.
Adults: W eek 1: 10 mg; weeks 2 and 3: 25 mg; then, 25-50 (maximum) mg/week until a total of 0.8-1 g has been administered. If client tolerates the dose and has improved, 50 mg may be given q 3-4 weeks for several months. Pediatric, 6-12 years: W eek 1: 2.5 mg; weeks 2 and 3: 6.25 mg; then, 12.5 mg/week until a total dose of 200-250 mg has been administered. Maintenance: 6.25-12.5 mg q 3-4 weeks.

Aurothioglucose Suspension Ratings

Overall Rating:

3.0***

 

(based on 2 reviews)

Effectiveness:

*

Ease of Use:

****~

Overall Satisfaction:

****

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Reviews

Aurothioglucose Suspension
3.0

Effectiveness: *

Ease of Use: ****

Overall Satisfaction: ****

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Patsy, Patsy - 03/06/2014

Assigned-risk plans. In an assigned-risk-type plan, each auto insurance QuotesChimp doing business in a state must write insurance for those who cannot otherwise obtain insurance, in a percentage equal to its share of the state's auto insurance market. Thus, if a company issues 12 percent of the auto insurance in the state, that company will have to provide insurance for 12 percent of those drivers who can't otherwise get insurance. In assigned-risk plans, the company that issues the policy services it as it would any of its other customers.

Aurothioglucose Suspension
3.5

Effectiveness: *

Ease of Use: *****

Overall Satisfaction: ****

Avatar_thumbnail

Adriana, Adriana - 01/12/2014

gate way to show people how to do this work by them selfs, im pinlnag on restoring the same car (Mustang Fastback 67), I found on a ranch and im really really mest using these videos as guides for all the problems I have. guys Very nice work, keep the bad jokes.