ZOLEDRONIC ACID (Injection) (Injectable)

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ZOLEDRONIC ACID (Injection) (Injectable) Drug and Prescription Information

ZOLEDRONIC ACID (Injection) (Injectable)

ZOLEDRONIC ACID (Injection) (Injectable) Medication Classification


ZOLEDRONIC ACID (Injection) (Injectable) Brandname


ZOLEDRONIC ACID (Injection) (Injectable) is used for the Treatment

Zoledronic Acid (ZOE-le-dron-ik AS-id) Treats high blood calcium levels (hypercalcemia) that sometimes occur in patients with cancer. Also treats bone damage caused by multiple myeloma and cancers that spread to the bone.

When To Not Use ZOLEDRONIC ACID (Injection) (Injectable)

You should not receive this medicine if you have had an allergic reaction to zoledronate, mannitol, or similar medicines such as alendronate (Fosamax®), etidronate (Didronel®), pamidronate (Aredia®), risedronate (Actonel®), or tiludronate (Skelid®), or if you are pregnant.

How Should You Use ZOLEDRONIC ACID (Injection) (Injectable)


  • Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
  • You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine. It may also be given by a home health caregiver.
  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins. It will take at least 15 minutes for you to receive one dose of this medicine.
  • If you are receiving this medicine for hypercalcemia, the medicine is usually given only once. If your doctor determines that you need additional doses, you will receive the medicine again after at least 7 days have passed. This treatment will continue until your body responds to the medicine.
  • If you are receiving this medicine for cancer treatment

Proper ZOLEDRONIC ACID (Injection) (Injectable) Storage

Store ZOLEDRONIC ACID (Injection) (Injectable) at room temperature away from sunlight and moisture unless otherwise stated by manufacturer's instructions or labelling. Keep ZOLEDRONIC ACID (Injection) (Injectable) and all medications out of the reach of children.

What To Avoid While Using ZOLEDRONIC ACID (Injection) (Injectable)

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using thalidomide (Thalomid®), antibiotics (such as amikacin (Amikin®), gentamicin (Garamycin®), streptomycin, tobramycin), or diuretics or "water pills" (such as furosemide, Lasix®).

ZOLEDRONIC ACID (Injection) (Injectable) Warnings

  • Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.
  • Make sure your doctor knows if you are breastfeeding, or if you have kidney disease, congestive heart failure, asthma, or an allergy to aspirin.
  • Your doctor will need to check your blood and urine at regular visits while you are using this medicine. Be sure to keep all appointments.

ZOLEDRONIC ACID (Injection) (Injectable) Side Effects

Call your doctor right away if you notice any of these side effects:

  • Decrease in how much or how often you urinate
  • Dry mouth, increased thirst, muscle cramps
  • Muscle spasms or tremors, loss of appetite, sleepiness
  • Painful urination, or blood in urine
  • Trouble breathing or chest pain
  • Unusual bleeding, bruising, or weakness
  • If you notice these less serious side effects, talk with your doctor:
  • Low fever, chills, bone or joint pain, general muscle aches
  • Mild nausea, vomiting, diarrhea, stomach pain, or constipation
  • Mild skin rash or itching
  • Pain, redness, swelling where the IV needle is placed
  • Red, irritated eyes
  • Trouble sleeping

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