Zoladex (Injection)

Questions | Reviews *

Zoladex and Hot flushes

    I received my last zoladex injection (three injections in total) last week and i had since had the worst hot flushes ever. I thought hot flushes were supposed to get better after the first month. Will the hot flushes ever go away? and af...
by anelisiwe bhebhe in United Kingdom, England, 08/07/2009

I have polycyctic ovaries, could the Zolades make my symptoms worse

I have a very bad hormonal imbalance resulting in polycystic ovaries that I really needed a cure because it made me commit suicide 7 times in two months and I was trying to then cure it. I have very bad facial hair and a serious depression but I felt ...
by Teresa Challis in Bath Somerset England, 04/04/2009

zoladex injection

I have been advised to go to the zoladex injections for 4 mths as i suffer with extrem pain for 3 weeks out the 28 day cycle.a week before my period, the week i am on and the week after the period stopped. I had a P.E left lung in May 2oo2 and i am ve...
by Mrs natalie Hallmark Jones in north wales uk, 07/02/2007

zoladex injection once missing cycle

I had the once zoladex series in April.  I choose not to get another series because of the side effects.  I have not had a menstrual cycle since the shot.  My breast are increasing and I am always fatigue.  Is this normal?  I ...
by angelique in atlanta, GA, 06/20/2007

Zoladex (Injection) Drug and Prescription Information

Zoladex (Injection)

Zoladex (Injection) Medication Classification

GOSERELIN (Injection)

Zoladex (Injection) Brandname


Zoladex (Injection) is used for the Treatment

Goserelin (GOE-se-rel-in) Treats symptoms of prostate cancer and breast cancer. In women, also treats endometriosis and other benign (not cancer) problems with the uterus. Sometimes used before or with other treatments.

When To Not Use Zoladex (Injection)

You should not receive this medicine if you have had an allergic reaction to goserelin or similar medicines such as gonadorelin, Factrel®, or LHRH. For a woman, you should not use this medicine for endometriosis or other benign problems if you are pregnant or breastfeeding, or if you have unusual vaginal bleeding that has not been checked by a doctor.

How Should You Use Zoladex (Injection)


  • Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
  • You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.
  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin near your stomach. This medicine may be given once every 28 days or once every 3 months. Your schedule depends on the reason you are using this medicine.
  • If you will also be receiving radiation therapy for cancer, you will start using this medicine 8 weeks before starting radiation treatment.
  • If a dose is missed:
  • This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.
  • Drugs and Foods to Avoid: Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
  • Make sure your doctor knows if you are also using oth

Proper Zoladex (Injection) Storage

Store Zoladex (Injection) at room temperature away from sunlight and moisture unless otherwise stated by manufacturer's instructions or labelling. Keep Zoladex (Injection) and all medications out of the reach of children.

What To Avoid While Using Zoladex (Injection)

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using other hormone medicines (such as Pregnyl®, Profasi®), a steroid (such as cortisone, prednisone), or medicine for seizures (such as Depakote®, Dilantin®).
  • Birth control pills, implants, patches, or shots may not work while you are using Zoladex®. To keep from getting pregnant, use another form of birth control. Other forms include condoms, a diaphragm, or contraceptive foam or jelly.

Zoladex (Injection) Warnings

  • Make sure your doctor knows if you have bone cancer, spinal cord (back) problems, trouble urinating, blood pressure problems, or pituitary gland problems.
  • Using this medicine while you are pregnant may harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. Use birth control during the time you are using this medicine and for at least 12 weeks after your last treatment. If you think you have become pregnant while using the medicine, tell your doctor right away.
  • For women, you will stop having menstrual periods while you are using this medicine. This is not an effective form of birth control. If you keep having normal periods while using this medicine, tell your doctor. If your periods do not return to normal after you stop using this medicine, tell your doctor.
  • When you first start using this medicine for cancer treatment, some of your symptoms might get worse for a short time. You might also have new symptoms. You might have bone pain, back pain, or trouble urinating. These problems should improve within a few weeks. Tell your doctor if you have any new or worse symptoms. Ask your doctor or nurse how to treat these symptoms.
  • This medicine might cause you to lose some bone density. Tell your doctor if you have risk factors for osteoporosis (thin or brittle bones). Some risk factors are alcohol abuse, smoking, a family history of osteoporosis, or using other medicines that might cause bone density loss, such as steroids or medicine for seizures.
  • Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.

Zoladex (Injection) Side Effects

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Lightheadedness or fainting
  • Swelling in your hands or feet
  • If you notice these less serious side effects, talk with your doctor:
  • Dryness or itching in your vagina
  • Headache, mood changes, mild depression, unusual tiredness
  • Hot flashes, sweating, change in breast size
  • Mild nausea, vomiting, diarrhea, loss of appetite
  • Trouble having sex or loss of interest in sex

Zoladex (Injection) Ratings

Overall Rating:



(based on 2 reviews)



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Zoladex (Injection)

Effectiveness: *

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Sylvie , New- brunswick, Canada - 03/18/2013

I got my first injection in November, at the cost of 1053.00$ for treatement of heavy bleeding and as preperation for a uterine ablation. It was supposed to stop my period for 3 months. My periods were lasting 7-10 days prior to the injection. My first period in December lasted 16 days, January's lasted 20 days. In February after 22 days of steady bleeding, I nearly fainted due to anemia and ended up in the ER where they put me on a birth control to stop the bleeding, it started again after 3 days. I'm currently on progesterone 3 times daily and though its slowed down the bleeding I still spot constantly.

I don't know what went wrong but it has done less than nothing for me. It seems that the process that usually causes my period to stop no longer happens. Considering all the side effects of hot flashes and mood swings I would not recommend this product.

Zoladex (Injection)

Effectiveness: *

Ease of Use: *

Overall Satisfaction: *


N.T, Evesham, UK - 07/01/2012

This injection has put me in considerable abdominal pain for five years, with massive weight gain and chronic constipation. I have been unable to work and my Oncology team in the UK say it is nothing to do with them. My GP is clueless and there is no resolve. I think it would be excellent as a lethal weapon. It has certainly finished my life off. It is now living hell due to the abdominal swelling I have.

I cannot rate give this product any psoitive rating so please ignore the stars.