VORICONAZOLE (Injection) (Injectable)

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VORICONAZOLE (Injection) (Injectable) Drug and Prescription Information

VORICONAZOLE (Injection) (Injectable)

VORICONAZOLE (Injection) (Injectable) Medication Classification


VORICONAZOLE (Injection) (Injectable) Brandname

Vfend I.V.

VORICONAZOLE (Injection) (Injectable) is used for the Treatment

Voriconazole (vor-i-KON-a-zole) Treats fungal infections.

When To Not Use VORICONAZOLE (Injection) (Injectable)

You should not use this medicine if you have had an allergic reaction to voriconazole, if you are also using rifampin (Rifadin®), carbamazepine (Tegretol®), phenobarbital, mephobarbital, sirolimus (Rapamune®), Seldane®, Hismanal®, cisapride (Propulsid®), quinidine (Quinidex®), ergot medicines (such as Wigraine®), or rifabutin (Mycobutin®), or if you are pregnant.

How Should You Use VORICONAZOLE (Injection) (Injectable)


  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins. This medicine needs to be given slowly over 1 to 2 hours.
  • A nurse or other trained health professional will give you this medicine.
  • You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.
  • This medicine is a powder that must be mixed with 2 liquids before using. Use the medicine as soon as possible after mixing.
  • Use a new needle and syringe each time you inject your medicine.
  • Never share your medicine with anyone.
  • If a dose is missed:
  • If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

Proper VORICONAZOLE (Injection) (Injectable) Storage

Store VORICONAZOLE (Injection) (Injectable) at room temperature away from sunlight and moisture unless otherwise stated by manufacturer's instructions or labelling. Keep VORICONAZOLE (Injection) (Injectable) and all medications out of the reach of children.

What To Avoid While Using VORICONAZOLE (Injection) (Injectable)

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using cyclosporine (Sandimmune®, Neoral®), tacrolimus (Prograf®), Prilosec®, Nexium®, vincristine (Oncovin®), vinblastine (Velban®), phenytoin (Dilantin®), a blood thinner such as warfarin (Coumadin®), a tranquilizer (such as alprazolam, diazepam, lorazepam), heart or blood pressure medicine (such as verapamil, Cardizem®, Lotrel®, Procardia®, Tiazac®), diabetes medicine (such as glipizide, glyburide, tolbutamide), medicines to treat HIV/AIDS (Agenerase®, Crixivan®, Invirase®, Norvir®, Sustiva®, Viracept®), or medicine to lower cholesterol (such as Lipitor®, Zocor®).

VORICONAZOLE (Injection) (Injectable) Warnings

  • Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.
  • Make sure your doctor knows if you are breastfeeding, if you have liver disease or kidney disease, or if you have had an allergic reaction to similar medicines (such as fluconazole, itraconazole, ketoconazole, Diflucan®, Sporanox®).
  • This medicine may cause vision problems. Avoid driving (especially at night), using machines, or doing anything else that could be dangerous if you cannot see well. Call your doctor if you have any vision changes or if bright lights bother your eyes.
  • Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments.
  • This medicine may make your skin more sensitive to sunlight. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds.

VORICONAZOLE (Injection) (Injectable) Side Effects

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in face or hands, swelling or tingling in the mouth or throat, tightness in chest, trouble breathing
  • Blistering, peeling, red skin rash
  • Change in how much or how often you urinate
  • Nausea, vomiting, loss of appetite, pain in the upper stomach
  • Yellow skin or eyes, dark-colored urine or pale stools
  • If you notice these less serious side effects, talk with your doctor:
  • Headache, fever
  • Redness, pain, or swelling where the IV needle is inserted

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