THIOGUANINE (Oral) (Tablet)

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THIOGUANINE (Oral) (Tablet) Drug and Prescription Information

THIOGUANINE (Oral) (Tablet)

THIOGUANINE (Oral) (Tablet) Medication Classification


THIOGUANINE (Oral) (Tablet) Brandname

THIOGUANINE (Oral) (Tablet) is used for the Treatment

Thioguanine (thye-oh-GWAH-neen) Used with other medicines to treat different kinds of leukemia.

When To Not Use THIOGUANINE (Oral) (Tablet)

You should not use this medicine if you have ever had an allergic reaction to thioguanine or mercaptopurine (Purinethol®).

How Should You Use THIOGUANINE (Oral) (Tablet)


  • This medicine, like all medicines used to treat cancer, is very strong. Make sure you understand why you are getting it and what the risks and benefits of treatment are. It is important for you to work closely with your doctor.
  • Your doctor will tell you how much medicine to use and how often. Make sure you understand your doctor's instructions.
  • Drink at least 6 to 8 large glasses of liquid every day while you are using this medicine.
  • If you vomit right after you take this medicine, call your doctor.
  • If a dose is missed:
  • Take the medicine as soon as possible, unless it is almost time for your next dose.
  • Skip the missed dose if it is almost time for your next regular dose.
  • You should not use two doses at the same time.

Proper THIOGUANINE (Oral) (Tablet) Storage

Store THIOGUANINE (Oral) (Tablet) at room temperature away from sunlight and moisture unless otherwise stated by manufacturer's instructions or labelling. Keep THIOGUANINE (Oral) (Tablet) and all medications out of the reach of children.

What To Avoid While Using THIOGUANINE (Oral) (Tablet)

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Avoid drinking alcohol while using thioguanine.
  • You should not use aspirin or any product that has aspirin in it (such as some cold medicines) unless you have talked to your doctor.
  • Talk to your doctor before having any vaccines (such as a flu shot).

THIOGUANINE (Oral) (Tablet) Warnings

  • If you are pregnant, talk to your doctor before you start your treatments.
  • Do not breastfeed while you are being treated with this medicine.
  • Do not get pregnant while you or your sexual partner are receiving thioguanine. Use an effective form of birth control while you are being treated with this medicine.
  • Tell your doctor if you have gout, liver disease, or a history of kidney stones.
  • Your doctor may want you to have blood tests on a regular schedule while you are using this medicine. Keep all of your appointments, or reschedule any appointments you miss.
  • You may get infections more easily while using this medicine. Stay away from crowds and people with colds, flu, or other infections.
  • This medicine may make your mouth sore and irritated. Use a soft-bristle toothbrush or mouth swab to brush your teeth.

THIOGUANINE (Oral) (Tablet) Side Effects

Call your doctor right away if you notice any of these side effects:

  • Dark-colored urine
  • Fever, sore throat, chills
  • Severe mouth sores that keep you from drinking liquids
  • Stomach pain, especially on the right side of your stomach
  • Uncontrollable nausea or vomiting
  • Unusual bruising or bleeding
  • Yellow skin or eyes
  • If you notice these less serious side effects, talk with your doctor:
  • Loss of appetite, mild diarrhea

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