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SULFADOXINE/PYRIMETHAMINE (Oral) (Tablet) Drug and Prescription Information


SULFADOXINE/PYRIMETHAMINE (Oral) (Tablet) Medication Classification




SULFADOXINE/PYRIMETHAMINE (Oral) (Tablet) is used for the Treatment

Pyrimethamine (peer-i-METH-a-meen), Sulfadoxine (sul-fa-DOX-een) Treats malaria.


You should not use this medicine if you have ever had an allergic reaction to any sulfa drug or to pyrimethamine. You should not use this medicine if you are breastfeeding, are in the last 3 months of pregnancy, or if you have severe kidney or liver disease or a blood disorder. This medicine should not be given to infants under 2 months of age.

How Should You Use SULFADOXINE/PYRIMETHAMINE (Oral) (Tablet)


  • Your doctor will tell you how much to take and how often. You should not use this medicine more often or in greater amounts than your doctor ordered.
  • This medicine may be taken with food or milk if it upsets your stomach.
  • Drink plenty of water while taking this medicine.
  • Take the medicine for as long as your doctor has ordered, even if you feel better.
  • If a dose is missed:
  • Take the missed dose as soon as possible.
  • If it is almost time for your next regular dose, wait until then to take the medicine and skip the missed dose.
  • You should not use two doses at the same time.

Proper SULFADOXINE/PYRIMETHAMINE (Oral) (Tablet) Storage

Store SULFADOXINE/PYRIMETHAMINE (Oral) (Tablet) at room temperature away from sunlight and moisture unless otherwise stated by manufacturer's instructions or labelling. Keep SULFADOXINE/PYRIMETHAMINE (Oral) (Tablet) and all medications out of the reach of children.

What To Avoid While Using SULFADOXINE/PYRIMETHAMINE (Oral) (Tablet)

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also taking chloroquine (Aralen®), or sulfa antibiotics such as Gantrisin®, Septra®, or Bactrim®.


  • If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.
  • Talk to your doctor if you have kidney or liver disease, or any blood problems.
  • If you develop a skin rash, stop taking this medicine immediately and call your doctor.
  • This medicine can make your skin more sensitive to sunlight. Avoid being in the sun for long periods of time and use sunscreen while you are taking this medicine.


Call your doctor right away if you notice any of these side effects:

  • Extreme tiredness
  • Painful urination
  • Skin rash, hives, or itching
  • Swollen face, lips, or tongue
  • Unexplained fever, sore throat, or cough
  • Unusual bleeding or bruising
  • Wheezing or trouble breathing
  • Yellowing of skin and eyes
  • If you notice these less serious side effects, talk with your doctor:
  • Diarrhea
  • Headache
  • Irritability, mood changes
  • Nausea, vomiting, or upset stomach


Overall Rating:



(based on 2 reviews)



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Effectiveness: ***

Ease of Use: **

Overall Satisfaction: ****


Rafaela, Rafaela - 01/15/2014

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