Paxil CR (Oral)

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Paxil CR (Oral) Drug and Prescription Information

Paxil CR (Oral)

Paxil CR (Oral) Medication Classification


Paxil CR (Oral) Brandname

Paxil, Paxil CR, Pexeva

Paxil CR (Oral) is used for the Treatment

Paroxetine (pa-ROX-e-teen) Treats depression, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, and generalized anxiety disorder. This medicine is a selective serotonin reuptake inhibitor (SSRI).

When To Not Use Paxil CR (Oral)

You should not use this medicine if you have had an allergic reaction to paroxetine, or if you are also using thioridazine (Mellaril®) or have taken an MAO inhibitor (Marplan®, Eldepryl®, Parnate®, or Nardil®) within the past 2 weeks.

How Should You Use Paxil CR (Oral)

Tablet, Long Acting Tablet, Liquid

  • Your doctor will tell you how much of this medicine to take and how often. Do not take more medicine or take it more often than your doctor tells you to.
  • You may take this medicine with or without food. This medicine is usually taken in the morning.
  • Shake the oral liquid well just before using. Measure the liquid medicine with a marked measuring spoon or medicine cup.
  • If a dose is missed:
  • If you miss a dose or forget to take your medicine, take it as soon as you can. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose.
  • Do not use extra medicine to make up for a missed dose.

Proper Paxil CR (Oral) Storage

Store Paxil CR (Oral) at room temperature away from sunlight and moisture unless otherwise stated by manufacturer's instructions or labelling. Keep Paxil CR (Oral) and all medications out of the reach of children.

What To Avoid While Using Paxil CR (Oral)

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using a blood thinner (Coumadin®), Tagamet®, tryptophan, sumatriptan (Imitrex®), theophylline (Theo-Dur®), any other medicine for depression (such as amitriptyline, Prozac®), medicine for heart rhythm problems (such as Quinaglute®, Quinidex®, Rythmol®, Tambocor®), diuretics ("water pills" such as furosemide), or phenothiazines (such as Phenergan®, Thorazine®).
  • Do not drink alcohol while you are using this medicine.

Paxil CR (Oral) Warnings

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, epilepsy, or a history of mania or bipolar disorder.
  • You may need to take this medicine for up to 4 weeks before you feel better. Keep using this medicine for the full treatment time. If you feel that the medicine is not working well, do not take more than your prescribed dose. Call your doctor for instructions.
  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.

Paxil CR (Oral) Side Effects

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in face or hands, swelling or tingling in the mouth or throat, tightness in chest, trouble breathing
  • Confusion, muscle weakness
  • Extreme weakness, lightheadedness, or fainting
  • Fast, slow, or irregular heartbeat
  • Unusual bleeding or bruising
  • If you notice these less serious side effects, talk with your doctor:
  • Loss of appetite
  • Mild weakness
  • Nausea, dry mouth, constipation
  • Problems with sex
  • Sweating
  • Tremors (shakiness)
  • Trouble sleeping

Paxil CR (Oral) Ratings

Overall Rating:



(based on 4 reviews)



Ease of Use:


Overall Satisfaction:




Paxil CR (Oral)

Effectiveness: ***

Ease of Use: *****

Overall Satisfaction: *


Lala, Lala - 01/13/2014

If you have taken anti-depressants to no effect, it is posisble that you have what is sometimes called atypical bi-polar disorder. It is much more difficult to diagnose than regular bi-polar disorder, as the symptoms are fairly mild. Most people just think they are depressed, as the manic symptoms are sometimes more mild and easy to miss.However, it is also posisble that your depression is caused by environmental factors, and not a chemical imbalance at all. In this case, I would recommend a psychotherapist, and possibly some lifestyle modifications.If you are really having difficulty functioning on a day to day basis due to depression, I highly recommend that you find a good psychopharmacologist. This is a specialty of psychiatry dealing mostly with treatment-resistant depression.As far as your comment that there are so many variables at play when it comes to depression and without addressing the right one or the right combination thereof, you're never going to solve anything, I absolutely completely agree. The job of your doctor is to determine what these variables are, and then to address them. If you really think that your doctor is blindly prescribing medication to you, I would highly suggest finding a new doctor, and posisble reporting your old doctor to an ethics committee.There ARE treatments for depression that work. The problem is determining what sort of depression you have, and what you would best respond to. Everyone's body chemistry is different, and not all anti-depressants are created equal. If you have not responded to the first medication you tried, that does not by ANY means that medication can't help. Just not that one.Don't give up hope. If you need more help, try the National Institute of Mental Health (google it) They can help with everything from finding a support group to finding a good doctor in your area, even if you are financially struggling.

Paxil CR (Oral)

Effectiveness: ****

Ease of Use: ***

Overall Satisfaction: ***


Chan, New York, NY - 11/27/2008

For 12 years I have been on the anti-depressant Paxil. It has turned my life around. Taking this medication is most beneficial if taken at the same time every day. If I miss a dose my eyes flutter and night sweats begin. It is also important to get enough sleep and drink plenty of fluids because it causes the same side effects. If I miss two or three doses the side effects are much more serious. They include night sweats, depression, dizziness and memory loss. This week alone I missed two pills. Durning this time I cried myself to sleep. If you take Paxil it is important to be careful about dosage. I am also not afraid anymore since taking Paxil.

Paxil CR (Oral)

Effectiveness: *

Ease of Use: *

Overall Satisfaction: *


Vicky Gupta, mississippi - 05/13/2008

The nightly leg contractions and increased anxiety add to my bad experience with Paxil, which has also put me in a wheelchair for a year due to tendonitis.