Ortho-Prefest (Oral)

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Ortho-Prefest (Oral) Drug and Prescription Information

Ortho-Prefest (Oral)

Ortho-Prefest (Oral) Medication Classification


Ortho-Prefest (Oral) Brandname

Ortho-Prefest, Prefest

Ortho-Prefest (Oral) is used for the Treatment

Estradiol (es-tra-DYE-ole), Norgestimate (nor-JES-ti-mate) Treats symptoms of menopause, such as hot flashes and vaginal changes. Also prevents osteoporosis.

When To Not Use Ortho-Prefest (Oral)

You should not take this medicine if you have had an allergic reaction to estrogen or progestin, or if you are pregnant. You should not take this medicine if you have unusual vaginal bleeding, breast cancer, uterine cancer, or a history of blood clots.

How Should You Use Ortho-Prefest (Oral)


  • This medicine comes in blister packs of two different colored tablets, pink and white. The tablets are arranged in rows of 3 pink tablets followed by 3 white tablets.
  • Take only one tablet each day, starting with the first pink tablet in the top row, and then moving from left to right as you take each daily tablet. You will take a pink tablet each day for 3 days, then a white tablet every day for 3 days, and so on.
  • If a dose is missed:
  • If you miss a dose or forget to take your medicine, take it as soon as you can. Then wait until the next day to take your medicine again. You should take only one tablet each day.
  • Do not use extra medicine to make up for a missed dose.

Proper Ortho-Prefest (Oral) Storage

Store Ortho-Prefest (Oral) at room temperature away from sunlight and moisture unless otherwise stated by manufacturer's instructions or labelling. Keep Ortho-Prefest (Oral) and all medications out of the reach of children.

What To Avoid While Using Ortho-Prefest (Oral)

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Ortho-Prefest (Oral) Warnings

  • After taking this medicine, if you discover that you are pregnant talk with your doctor right away.
  • Make sure your doctor knows if you have gallbladder disease.
  • Estrogen has been shown to increase the risk of cancer. Talk with your doctor about the risks and benefits of taking this medicine.

Ortho-Prefest (Oral) Side Effects

Call your doctor right away if you notice any of these side effects:

  • Abnormal vaginal bleeding
  • Breast lumps
  • Fever, chills, sore throat, or runny nose
  • Pain in the calves or chest
  • Shortness of breath or coughing up blood
  • If you notice these less serious side effects, talk with your doctor:
  • Dizziness
  • Headache
  • Menstrual cramps
  • Nausea or gas
  • Pain in the breasts, back, stomach, joints, or muscles
  • Runny nose
  • Tiredness

Ortho-Prefest (Oral) Ratings

Overall Rating:



(based on 2 reviews)



Ease of Use:


Overall Satisfaction:




Ortho-Prefest (Oral)

Effectiveness: ***

Ease of Use: ****

Overall Satisfaction: **


Mark, Mark - 01/10/2014

Amanda I pray that you will have answers to your hlaeth issues soon. That is a very long time to go without answers, especially when you are a mom and have to put on a smile for your children every day. It is very frustrating to not know what is going on. I pray that God will heal you and for the blessing of doctors who will have the knowledge to help you. Keep your faith; God is an amazing healer! Don't worry about the couponing; but please keep us updated about your hlaeth.