Oncaspar (Injection)

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Oncaspar (Injection) Drug and Prescription Information

Oncaspar (Injection)

Oncaspar (Injection) Medication Classification


Oncaspar (Injection) Brandname


Oncaspar (Injection) is used for the Treatment

Pegaspargase (peg-AS-par-jase) Treats cancer of the white blood cells (lymphoblastic leukemia).

When To Not Use Oncaspar (Injection)

You should not use this medicine if you have inflammation of the pancreas (pancreatitis), a bleeding problem caused by taking L-asparaginase (Elspar®), or if you have ever had an allergic reaction to pegaspargase.

How Should You Use Oncaspar (Injection)


  • An IM injection is a shot given in your muscle (upper arm, thigh, buttocks). An IV infusion is a bag of medicine connected to a long tube with a needle on the end of it. The needle is placed in your vein, usually inside your elbow or on the back of your hand or wrist. The medicine slowly drips from the bag through the tube and into your vein.
  • Your doctor will prescribe your exact dose and tell you how often it is to be given.
  • This medicine should be given by a person trained to give cancer chemotherapy medicine, such as a home care or oncology nurse.
  • Avoid getting this medicine on the skin or in the eyes or breathing in the vapors.
  • If this medicine gets on your skin or in your eyes, rinse the area for at least 15 minutes with large amounts of water.
  • You should not use the medicine if it becomes cloudy or changes color. Do not shake the vial (bottle).
  • If a dose is missed:
  • This medicine needs to be given on a regular schedule. If you miss a dose, contact your doctor for instructions.

Proper Oncaspar (Injection) Storage

Store Oncaspar (Injection) at room temperature away from sunlight and moisture unless otherwise stated by manufacturer's instructions or labelling. Keep Oncaspar (Injection) and all medications out of the reach of children.

What To Avoid While Using Oncaspar (Injection)

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are taking any medicine that affects blood clotting, such as aspirin, ibuprofen (Motrin®), warfarin (Coumadin®), or dipyridamole (Persantine®).

Oncaspar (Injection) Warnings

  • If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.
  • Medicines that treat cancer can depress your body's immune system, which makes it easier to get infections. Try to stay away from people with colds or the flu.
  • This medicine can increase the level of uric acid in your blood (which can worsen gout).
  • Pegaspargase can increase the level of sugar in your blood and can worsen diabetes.
  • You will need to stay at your doctor's office or clinic for one hour after receiving this medicine to make sure you do not have a reaction to it.

Oncaspar (Injection) Side Effects

Call your doctor right away if you notice any of these side effects:

  • Trouble breathing, rash or hives
  • Swelling of the lips or tongue
  • Severe nausea and vomiting with stomach pain
  • Unexplained fever, chills
  • Yellowing of the skin or eyes
  • Unusual bleeding and bruising
  • Pain or numbness in the legs
  • If you notice these less serious side effects, talk with your doctor:
  • Weakness, tired feeling
  • Loss of appetite, nausea and vomiting
  • Injection site pain

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