Mesnex (Injection)

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Mesnex (Injection) Drug and Prescription Information

Mesnex (Injection)

Mesnex (Injection) Medication Classification

MESNA (Injection)

Mesnex (Injection) Brandname


Mesnex (Injection) is used for the Treatment

Mesna (MES-na) Protects the bladder from damage that may be caused by some cancer medicines.

When To Not Use Mesnex (Injection)

You should not receive this medicine if you have had an allergic reaction to mesna or related medicines (such as thimerosal, spironolactone, Purinethol®, Tapazole®, Aldactone®).

How Should You Use Mesnex (Injection)


  • You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.
  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins. Your doctor may also want you to use Mesnex® tablets 2 hours before and 6 hours after your injection.
  • Drink at least 1 quart (32 ounces) of liquid every day to pass more urine while you are using this medicine. This will keep your kidneys and bladder working well and help prevent problems.
  • You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.
  • Use a new needle and syringe each time you inject your medicine.
  • Never share your medicine with anyone.
  • If a dose is missed:
  • This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

Proper Mesnex (Injection) Storage

Store Mesnex (Injection) at room temperature away from sunlight and moisture unless otherwise stated by manufacturer's instructions or labelling. Keep Mesnex (Injection) and all medications out of the reach of children.

What To Avoid While Using Mesnex (Injection)

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using cyclophosphamide (Cytoxan®).

Mesnex (Injection) Warnings

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have an autoimmune disorder (such as rheumatoid arthritis or lupus).
  • You may still have bladder problems while using this medicine. Your doctor will need to test your morning urine before you receive your cancer treatments. If you have pink or red urine, tell your doctor right away.
  • This medicine may affect the results of certain medical tests.

Mesnex (Injection) Side Effects

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Fever
  • Unusual bleeding, bruising, or weakness
  • If you notice these less serious side effects, talk with your doctor:
  • Headache
  • Nausea, vomiting, diarrhea, constipation, loss of appetite
  • Pain, redness, or swelling where the IV needle is placed
  • Warmth or redness in your face, neck, arms, or upper chest

Mesnex (Injection) Ratings

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