Trimipramine maleate

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Trimipramine maleate
Trimipramine maleate (Surmontil)
Trimipramine maleate
(try- MIP-rah-meen)
Pregnancy Category: C Apo-Trimip Novo-Tripramine Nu-Trimipramine Rhotrimine Surmontil (Rx)

Classification: Antidepressant, tricyclic

See Also: See also Antidepressants, Tricyclic .

Action/Kinetics: Causes moderate anticholinergic and orthostatic hypotensive effects and significant sedative effects. Effective plasma levels: 180 ng/mL. Time to reach steady state: 2-6 days. t 1/2: 7-30 hr.

Uses: Treatment of symptoms of depression. PUD. Seems more effective in endogenous depression than in other types of depression.

Contraindications: Use in children less than 12 years of age.

How Supplied: Capsule: 25 mg, 50 mg, 100 mg

?Capsules Antidepressant.
Adults, outpatients, initial: 75 mg/day in divided doses up to 150 mg/day, but not to exceed 200 mg/day; maintenance: 50-150 mg/day. Total dose can be given at bedtime. Adults, hospitalized, initial: 100 mg/day in divided doses up to 200 mg/day. If no improvement in 2-3 weeks, increase to 250-300 mg/day. Adolescent/geriatric clients, initial: 50 mg/day up to 100 mg/day. Not recommended for children.

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