Trientine hydrochloride Dosage, Interactions, Side Effects, How to Use

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Need Trientine hydrochloride drug manufacturers details in india hi iam kishore. my brother is suffering with wilson desease. and doctors suggested to take Trientine hydrochloride medicine. and tht medicine is not available in bangalore and hyderabad in India. so please tell me the drug manufacturers informatio... by kancherla kishore, 01/04/2006

Trientine hydrochloride
Trientine hydrochloride (Syprine)
Trientine hydrochloride
( TRY-en-teen)
Pregnancy Category: C Syprine (Rx)

Classification: Chelating agent

Action/Kinetics: A chelating agent that binds copper, thus facilitating its excretion from the body.

Uses: Wilson's disease (a metabolic defect resulting in excess copper accumulation) who are intolerant of penicillamine.

Contraindications: Use in cystinuria, rheumatoid arthritis, biliary cirrhosis.

Special Concerns: Use with caution during lactation. Safety and effectiveness in children have not been determined although the drug has been used in children as young as 6 years of age.

Side Effects: Iron deficiency anemia, SLE.

How Supplied: Capsule: 250 mg

Dosage
?Capsules Wilson's disease.
Adults, initial: 750 mg/day-1.25 g/day in divided doses b.i.d., t.i.d., or q.i.d.; then, may increase to a maximum of 2 g/day. Children less than 12 years of age, initial: 500-750 mg/day in divided doses b.i.d., t.i.d., or q.i.d.; then, may increase to a maximum of 1.5 g/day.