Tamsulosin hydrochloride Dosage, Interactions, Side Effects, How to Use

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Why stop taking tamsulosin for a cataract operation? My father, aged 85, has prostate cancer and is taking tamsulosin hydrochloride. he has an appointment for a cataract operation on his left eye and has been told to stop taking this tablet for 10 days before the operation. Why has he been asked to stop... by Cathy Harrison in UK, 04/11/2008

Post Pregnancy Treatment of Atonic Bladder by tamsulosin hydrochloride What are side effects for infant when this drug is recommended for feeding mothers by apoorva in Mumbai , India, 12/02/2005

Tamsulosin hydrochloride
Tamsulosin hydrochloride (Flomax)
Tamsulosin hydrochloride
(tam- SOO-loh-sin)
Pregnancy Category: B Flomax (Rx)

Classification: Alpha-1 adrenergic blocking agent

Action/Kinetics: Blockade of alpha-1 receptors (probably alpha 1A) in prostate results in relaxation of smooth muscles in bladder neck and prostate; thus, urine flow rate is improved and there is a decrease in symptoms of BPH. Food interferes with the rate of absorption. t 1/2, elimination: 5-7 hr. Significantly bound to plasma proteins. Extensively metabolized in liver; excreted through urine and feces.

Uses: Treatment of signs and symptoms of BPH. Rule out prostatic carcinoma before using tamsulosin.

Contraindications: Use to treat hypertension, with other alpha-adrenergic blocking agents, or in women or children.

Special Concerns: Use with caution with concurrent administration of warfarin.

Side Effects: Body as a whole: Headache, infection, asthenia, back pain, chest pain. CV: Postural hypotension, syncope. GI: Diarrhea, nausea, tooth disorder. CNS: Dizziness, vertigo, somnolence, insomnia, decreased libido. Respiratory: Rhinitis, pharyngitis, increased cough, sinusitis. GU: Abnormal ejaculation. Miscellaneous: Amblyopia.

Overdose Management: Symptoms: Hypotension. Treatment: Keep client in supine position to restore BP and normalize HR. If this is inadequate, consider IV fluids. Vasopressors may also be used; monitor renal function.

Drug Interactions: Cimetidine causes significant in clearance of tamsulosin.

How Supplied: Capsules: 0.4 mg

Dosage
?Capsules Benign prostatic hypertrophy.
Adult males: 0.4 mg daily given about 30 min after same meal each day. If, after 2 to 4 weeks, clients have not responded, dose can be increased to 0.8 mg daily.