Promazine hydrochloride Dosage, Interactions, Side Effects, How to Use

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Overdose in elderly care My Mum is 82 and has Alzheimers. She has been in respite care for the past two weeks and was given promazine on a regular basis (5ml morning and evening). She had a fall and split her head open. Two days later she was rushed to hospital unable to be r... by Kate M in Manchester UK, 06/05/2006

How long should promozine be taken for? My Mother has been taking Promazine for over 7yrs & now has been advised that she should have been on it for 2 and a half years max.She is currently suffering bad side effects,her new doctor says its because of the extensive useage of this drug & she ... by Jenny H in england, 05/19/2006

How long should promozine be taken for? My Mother has been taking Promazine for over 7yrs & now has been advised that she should have been on it for 2 and a half years max.She is currently suffering bad side effects,her new doctor says its because of the extensive use of this drug & she has... by Jenny Herbert in england, 05/19/2006

Promazine hydrochloride
Promazine hydrochloride (Sparine)
Promazine hydrochloride
( PROH-mah-zeen)
Pregnancy Category: C Sparine (Rx)

Classification: Antipsychotic, dimethylaminopropyl-type phenothiazine

See Also: See also Antipsychotic Agents, Phenothiazines .

Action/Kinetics: Significant anticholinergic, sedative, and hypotensive effects; moderate antiemetic effect; and weak extrapyramidal effects. Ineffective in reducing destructive behavior in acutely agitated psychotic clients.

Uses: Psychotic disorders.

Special Concerns: Safe use during pregnancy has not been established. Dosage has not been established in children less than 12 years of age. Geriatric, emaciated, and debilitated clients may require a lower initial dosage.

How Supplied: Injection: 25 mg/mL, 50 mg/mL; Tablet: 50 mg

Dosage
?Tablets Psychotic disorders.
Adults: 10-200 mg q 4-6 hr; adjust dose as needed and tolerated. Total daily dose should not exceed 1,000 mg. Pediatric, 12 years and older: 10-25 mg q 4-6 hr; adjust dose as needed and tolerated.
?IM Psychotic disorders, severe and moderate agitation.
Adults, initial: 50-150 mg; if desired calming effect is not seen after 30 min, give additional doses up to a total of 300 mg. Maintenance: 10-200 mg q 4-6 hr as needed and tolerated. Switch to PO therapy as soon as possible. Pediatric over 12 years: 10-25 mg q 4-6 hr for chronic psychotic disorders (maximum dose: 1 g/day).