Penicillin G potassium for injection


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Penicillin g Potassium


Where Can i buy penicillin g potassium for injection from??
by Amy in United States, 10/31/2007

Penicillin G potassium for injection
Penicillin G potassium for injection (Pfizerpen)
Penicillin G Potassium/Sodium
(pen-ih- SILL-in)
Pregnancy Category: B Pfizerpen (Rx)
Penicillin G (Aqueous) sodium for injection
Penicillin G (Aqueous) sodium for injection
Penicillin G Potassium/Sodium
(pen-ih- SILL-in )
Pregnancy Category: B (Rx)

Classification: Antibiotic, penicillin

See Also: See also Anti-Infectives and Penicillins .

Action/Kinetics: The first choice for treatment of many infections due to low cost. Rapid onset makes it especially suitable for fulminating infections. Is neither penicillinase resistant nor acid stable. Peak plasma levels: IM or SC, 6-20 units/mL after 15-30 min t 1/2: 30 min.

Uses: Streptococci of groups A, C, G, H, L, and M are sensitive to penicillin G. High serum levels are effective against streptococci of the D group.

Additional Side Effects: Rapid IV administration may cause hyperkalemia and cardiac arrhythmias. Renal damage occurs rarely.

Additional Drug Interactions: Aspirin, ethacrynic acid, furosemide, indomethacin, sulfonamides, or thiazide diuretics may compete with penicillin G for renal tubular secretion prolongation of serum t 1/2 of penicillin

How Supplied: Penicillin G potassium for injection: Injection: 1 million U/50 mL, 2 million U/50 mL, 3 million U/50 mL; Powder for injection: 1 million U, 5 million U, 10 million U, 20 million U Penicillin G (Aqueous) sodium for injection: Powder for injection: 5 million U

Dosage
?Penicillin G Potassium and Sodium Injections (IM, Continuous IV Infusion) Serious streptococcal infections (empyema, endocarditis, meningitis, pericarditis, pneumonia).
Adults: 5-24 million units/day in divided doses q 4 to 6 hr. Pediatric: 150,000 units/kg/day given in equal doses q 4 to 6 hr. Infants over 7 days of age: 75,000 units/kg/day in divided doses q 8 hr. Infants less than 7 days of age: 50,000 units/kg/day given in divided doses q 12 hr. For group B streptococcus, give 100,000 units/kg/day.
Meningococcal meningitis/septicemia.
Adults: 1-2 million units IM q 2 hr or 20-30 million units/day continuous IV drip for 14 days or until afebrile for 7 days. Or, 200,000-300,000 units/kg/day q 2-4 hr in divided doses for a total of 24 doses.
Meningitis due to susceptible strains of Pneumococcus or Meningococcus.
Children: 250,000 units/kg/day divided in equal doses q 4 to 6 hr for 7 to 14 days (maximum daily dose: 12-20 million units). Infants over 7 days of age: 200,000-300,0000 units/kg/day divided into equal doses given q 6 hr. Infants less than 7 days of age: 100,000-150,000 units/kg/day.
Anthrax.
Adults: A minimum of 5 million units/day (up to 12-20 million units have been used).
Clostridial infections.
Adults: 20 million units/day used with an antitoxin.
Actinomycosis.
Adults: C ervicofacial: 1-6 million units/day. Thoracic and abdominal disease: initial, 10-20 million units/day divided into equal doses given q 6 hr IV for 6 weeks followed by penicillin V, PO, 500 mg q.i.d. for 2-3 months.
Rat-bite fever, Haverhill fever.
Adults: 12-20 million units/day q 4 to 6 hr for 3-4 weeks. Children: 150,000-250,000 units/kg/day in equal doses q 4 hr for 4 weeks.
Endocarditis due to Listeria.
Adults: 15-20 million units/day q 4 to 6 hr for 4 weeks.
Endocarditis due to Erysipelothrix rhusiopathiae.
Adults: 12-20 million units/day q 4 to 6 hr for 4-6 weeks.
Meningitis due to Listeria.
Adults: 15-20 million units/day q 4 to 6 hr for 2 weeks.
Pasteurella infections causing bacteremia and meningitis.
Adults: 4-6 million units/day q 4 to 6 hr for 2 weeks.
Severe fusospirochetal infections of the oropharynx, lower respiratory tract, and genital area.
Adults: 5-10 million units/day q 4 to 6 hr.
Pneumococcal infections causing empyema.
Adults: 5-24 million units/day in divided doses q 4-6 hr.
Pneumococcal infections causing meningitis.
Adults: 20-24 million units/day for 14 days.
Pneumococcal infections causing endocarditis, pericarditis, peritonitis, suppurative arthritis, osteomyelitis, mastoiditis.
Adults: 12-20 million units/day for 2-4 weeks.
Adjunct with antitoxin to prevent diphtheria.
Adults: 2-3 million units/day in divided doses q 4 to 6 hr for 10-12 days. Children: 150,000-250,000 units/kg/day in equal doses q 6 hr for 10 days.
Neurosyphilis.
Adults: 18-24 million units/day (3-4 million units q 4 hr) for 10-14 days (can be followed by benzathine penicillin G, 2.4 million units IM weekly for 3 weeks).
Disseminated gonococcal infections.
Adults: 10 million units/day q 4 to 6 hr (for meningococcal meningitis/septicemia, give q 3 hr). Children, less than 45 kg: Arthritis, 100,000 units/kg/day in 4 equally divided doses for 7 to 10 days. Endocarditis: 250,000 units/kg/day in equal doses q 4 hr for 4 weeks. Meningitis: 250,000 units/kg/day in equal doses q 4 hr for 10 to 14 days. Children, over 45 kg: Arthritis, endocarditis, meningitis: 10 million units/day in 4 equally divided doses (duration depends on type of infection).
Congenital syphilis after the newborn period.
50,000 units/kg IV q 4-6 hr for 10-14 days.
Symptomatic or asymptomatic congenital syphilis in infants.
Infants: 50,000 units/kg IV q 12 hr the first 7 days; then, q 8 hr for a total of 10 days. Children: 50,000 units/kg q 4 to 6 hr for 10 days.

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