Oxybutynin chloride

Questions | Reviews ***

Oxybutynin 2.5 mgs

Hi I was prescribed Oxybutynin 2.5mgs 1 x tds by my GP as I have presented with UTI symptoms but have a clear MSU. The symptoms disappeared for about 5 days but now are back again and I am wondering whether this is an adverse reaction to the tablets o...
by Valerie in UK, 10/03/2006

Interstitial cystitis and reg:IC

I have interstitial cystitis and my family doctor precribed this medicine for me.. please advise me if this medicine is safe to take with my bladder condition.. Thank you... anne
by anne in Niagara Falls Canada, 03/02/2006

side effect Constipation

I have been taking ovybutybnin 10 mg for at least 3-4 months. I am constipated. So much so that I had to dig out the dry marbled pieces of stool! This has happened twice. Doctor sent me to a gastrologist and in Feb. I will get an upper and then 10 day...
by Ruth Poore in Emmaus PA 18049, 01/24/2007

mode of action of oxybutynin chloride

hi, this is ghulam dastagir from PAKISTAN. i want to know that how does oxybutynin chloride work in our body and what is its mode of action?
by ghulam dastagir jarwar in pakistan, 11/09/2005

bladder control

  I am a C 5-6 Quad of 21 years. I've always worn a condom catheter along with a leg bag. I have no control over when my bladder empties.  I recentley had a kidney removed. My Dr. just started me on Oxybutinin Chloride to help control my...
by Kedric Hubbard in Norfolk, Va., 02/17/2009

Oxybutynin chloride
Oxybutynin chloride (Ditropan)
Oxybutynin chloride
(ox-ee- BYOU-tih-nin)
Pregnancy Category: B Albert Oxybutynin Apo-Oxybutynin Ditropan Ditropan XL Gen-Oxybutynin Novo-Oxybutynin Nu-Oxybutyn Oxybutyn PMS-Oxybutynin (Rx)

Classification: Antispasmodic

Action/Kinetics: Causes increased vesicle capacity, decreases frequency of uninhibited contractions of the detrusor muscle, and delays initial urgency to void by exerting a direct antispasmodic effect. Has no effect at either the neuromuscular junction or autonomic ganglia. Has 4-10 times the antispasmodic effect of atropine but only one-fifth the anticholinergic activity. Onset: 30-60 min; Time to peak effect: 3-6 hr; duration: 6-10 hr. Eliminated through the urine.

Uses: Neurogenic bladder disease characterized by urinary retention, urinary overflow, incontinence, nocturia, urinary frequency or urgency, reflex neurogenic bladder.

Contraindications: Glaucoma (angle closure), untreated narrow anterior chamber angles, GI obstruction, paralytic ileus, intestinal atony (in elderly or debilitated), megacolon, toxic megacolon complicating ulcerative colitis, severe colitis, myasthenia gravis, obstructive uropathy, unstable CV status in acute hemorrhage.

Special Concerns: Use with caution when increased cholinergic effect is undesirable and in the elderly. Safe use in children less than 5 years of age has not been determined. Use with caution in geriatric clients; during lactation; in clients with autonomic neuropathy, renal, or hepatic disease; and in clients with hiatal hernia with reflex esophagitis. Heat stroke and fever (due to decreased sweating) may occur if given at high environmental temperatures.

Side Effects: GI: N&V, constipation, bloated feeling, decreased GI motility. CNS: Drowsiness, insomnia, weakness, dizziness, restlessness, hallucinations. EENT: Dry mouth, decreased lacrimation, mydriasis, amblyopia, cycloplegia. CV: Tachycardia, palpitations, vasodilation. Miscellaneous: Decreased sweating, urinary hesitancy and retention, impotence, suppression of lactation, severe allergic reactions drug idiosyncrasies, urticaria, and other dermal manifestations. NOTE: The drug may aggravate symptoms of prostatic hypertrophy, hypertension, coronary heart disease, CHF, hyperthyroidism, cardiac arrhythmias, and tachycardia.

Overdose Management: Symptoms: Intense CNS disturbances (restlessness, psychoses), circulatory changes (flushing, hypotension) and failure, respiratory failure, paralysis, coma. Treatment: Stomach lavage, physostigmine (0.5-2 mg IV; repeat as necessary up to maximum of 5 mg). Supportive therapy, if necessary. Counteract excitement with sodium thiopental (2%) or chloral hydrate (100-200 mL of 2% solution) rectally. Artificial respiration may be necessary if respiratory muscles become paralyzed.

Drug Interactions: See Cholinergic Blocking Agents.

How Supplied: Syrup: 5 mg/5 mL; Tablet: 5 mg; Tablet, Long-Acting: 5 mg, 10 mg, 15 mg

?Syrup, Tablets
Adults: 5 mg b.i.d.-t.i.d. Maximum dose: 5 mg q.i.d. Children, over 5 years: 5 mg b.i.d. Maximum dose: 5 mg t.i.d.
?Tablets, Long-Acting
Adults, initial: 5 mg once daily. Increase, in 5- mg increments, up to a maximum of 30 mg/day.

Oxybutynin chloride Ratings

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Oxybutynin chloride

Effectiveness: ***

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Overall Satisfaction: ***


Nancy, Salt lake,utah - 10/01/2011

Works really well to control bladder spasms and pain in the right dose. I was first ordered 5 mg twice a day and it wasn't very effective but when the dose was increased I had a good response!