Morphine hydrochloride

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morphine dosage

A  person is taking oxycodone 1-2 tablets q 4-6 hours, and morphine 10mg TID for several years for headache pain. Person now has multiple rib fractures. (ribs 2,3 qnd 4) Pain is not under control. Is it safe for patient to have any more pain meds...
by vicky in Madison, WI, 03/17/2008

Difference between Morphine hydrochloride and Morphine sulfate

Is there a differance between morpine hydrochloride and morpine sulfate. I am currently taking 200mg twice daily of morphine sulfate for severe chronic neck pain. Is it just a time release differance or are there differant applications for both of the...
by Mark Riggs in Grand Rapids Michigan USA, 03/30/2006

morphine and water for injection

I am a student nurse and i would like to know how much water for injection would be added to 2.5mg of morphine hydochloride when give IM or SC?
by marcia coutts in Scotland (UK), 08/26/2008

moraphine over dose with other meds

My mother was given 60 millagrams a day of moraphine/ mc and a anti anzity med 4 millagrams a day with compazine. She became a zomby and died dehdrated in just 4 days. I believe the drugs killed her before the lung disease did?
by fran in usa california, 06/10/2007

Tooth decay due to morphine use????

Iwas on this drug for 3plus years,am clean now,but through process of getting clean ,my teeth literally fell apart.I had nice teeth before my injury,QUESTION;can my teeth falling apart be attributed to this drug s consumption?I,AT M.Y WORST TIMES WAS ...
by Daniel Currie in Canada, 11/14/2007

Morphine hydrochloride
Morphine hydrochloride (Morphitec)
( MOR-feen)
Pregnancy Category: C Morphitec-1, -5, -10, -20 M.O.S. M.O.S.-S.R. (Rx)
Morphine sulfate
Morphine sulfate (Astramorph PF)
( MOR-feen SUL-fayt)
Pregnancy Category: C Astramorph PF Duramorph Infumorph Kadian M-Eslon M.O.S.-Sulfate MS Contin MSIR OMS Concentrate Oramorph SR RMS RMS Rectal Suppositories Roxanol Roxanol 100 Roxanol Rescudose Roxanol-T Roxanol UD Statex (C-II) (Rx)

Classification: Narcotic analgesic, morphine type

See Also: See also Narcotic Analgesics .

Action/Kinetics: Morphine is the prototype for opiate analgesics. Onset: approximately 15-60 min, based on epidural or intrathecal use. Peak effect: 30-60 min. Duration: 3-7 hr. t 1/2: 1.5-2 hr. Oral morphine is only one-third to one-sixth as effective as parenteral products.

Uses: Intrathecally, epidurally, PO (including sustained-release products), or by continuous IV infusion for acute or chronic pain. In low doses, morphine is more effective against dull, continuous pain than against intermittent, sharp pain. Large doses, however, will dull almost any kind of pain. Preoperative medication. To facilitate induction of anesthesia and reduce dose of anesthetic. Investigational: Acute LV failure (for dyspneic seizures) and pulmonary edema. Morphine should not be used with papaverine for analgesia in biliary spasms but may be used with papaverine in acute vascular occlusions.

Additional Contraindications: Epidural or intrathecal morphine: If infection is present at injection site, anticoagulant therapy, bleeding diathesis, if client has received parenteral corticosteroids within the past 2 weeks. Morphine injection: Heart failure secondary to chronic lung disease, cardiac arrhythmias, brain tumor, acute alcoholism, delirium tremens, convulsive states. Immediate release oral solution of morphine: Respiratory insufficiency, severe CNS depression, heart failure secondary to chronic lung disease, cardiac arrhythmias, increased intracranial or CSF pressure, head injuries, brain tumor, acute alcoholism, delirium tremens, after biliary tract surgery, suspected surgical abdomen, convulsive disorders, surgical anastomosis, with MAO inhibitors or within 14 days of these drugs.

Special Concerns: May increase the length of labor. Clients with known seizure disorders may be at greater risk for morphine-induced seizure activity. Respiratory depression may be delayed up to 24 hr after epidural or intrathecal use.

Additional Drug Interactions: Amitriptyline / CNS and respiratory depression Cimetidine / CNS and respiratory depression Clomipramine / CNS and respiratory depression Nortriptyline / CNS and respiratory depression Warfarin / Warfarin anticoagulant effect

How Supplied: Morphine hydrochloride: Syrup: 1 mg/mL, 5 mg/mL, 10 mg/mL, 20 mg/mL; Concentrate: 20 mg/mL, 50 mg/mL; Suppository: 10 mg, 20 mg, 30 mg; Tablets: 10 mg, 20 mg, 40 mg, 60 mg; Slow-release tablets: 30 mg, 60 mg. Morphine sulfate: Capsule: 15 mg, 30 mg; Capsule, Extended Release: 20 mg, 50 mg, 100 mg; Oral Solution: 10 mg/2.5 mL, 10 mg/5 mL, 20 mg/5 mL, 20 mg/mL, 30 mg/1.5 mL, 100 mg/5 mL; Injection: 0.5 mg/mL, 1 mg/mL, 2 mg/mL, 4 mg/mL, 5 mg/mL, 8 mg/mL, 10 mg/mL, 15 mg/mL, 25 mg/mL, 50 mg/mL; Suppository: 5 mg, 10 mg, 20 mg, 30 mg; Tablet: 15 mg, 30 mg; Tablet, Controlled Release: 15 mg, 30 mg, 60 mg, 100 mg, 200 mg; Tablets, Soluble: 10 mg, 15 mg, 30 mg

?Capsules, Tablets, Oral Solution, Soluble Tablets, Syrup Analgesia.
10-20 mg (solution) or 15-30 mg (tablets) q 4 hr.
?Sustained-Release Tablets Analgesia.
Titrate first to analgesia using an immediate release product and then transfer to a long-acting product. To convert from immediate release PO morphine to controlled release PO morphine, give the total daily PO morphine dose q 24 hr if using Kadian; or, 1/2 the total daily PO morphine dose q 12 hr if using Oramorph SR, Kadian, or MS Contin; or, 1/3 the total daily PO morphine dose q 8 hr if using MS Contin. If Kadian is selected as the initial product, start with either 20 mg q 12 hr or 40 mg once daily. The MS Contin 200 mg tablet is only for narcotic tolerant clients requiring daily morphine equivalent doses of 400 or more mg.
?IM, SC Analgesia.
Adults: 10-20 mg/70 kg q 4 hr as needed; pediatric: 100-200 mcg/kg q 4 hr, up to a maximum of 15 mg/dose.
8-15 mg. For very severe pain, give additional smaller amounts q 3-4 hr.
?IV Infusion Analgesia.
Adults: 2.5-15 mg/70 kg in 4-5 mL of water for injection (should be administered slowly over 4-5 min).
?IV Infusion, Continuous Analgesia.
Adults: 0.1-1 mg/mL in D5W by a controlled-infusion pump.
?IV Open-heart surgery.
0.5 - 3 mg/kg as the sole anesthetic or with a suitable anesthetic. Give oxygen and adequate ventilation.
?Rectal Suppositories
Adults: 10-20 mg q 4 hr or as directed by provider.
Adults: 0.2-1 mg as a single daily injection.
Initial: 5 mg/day in the lumbar region; if analgesia is not manifested in 1 hr, increasing doses of 1-2 mg can be given, not to exceed 10 mg/day. For continuous infusion, 2-4 mg/day with additional doses of 1-2 mg if analgesia is not satisfactory.

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Morphine hydrochloride

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Jason, Arkansas - 01/08/2014

I take this at night to ease back and neck pain and I as others I have read posts from feel this medication is a complete waste of time, effort and money. I feel no affect at all from it, it doesn't seem to ease the pain or allow me to rest, I still have to take other medications with it.