Methadone hydrochloride

Questions | Reviews

methadone hcl 10 mg

need to know about side effects --- effects on my heart
by chuck in los angeles ca., 12/07/2006

Side effects of Methadone hcl 5 mg 4x daily

My doctor prescribed this dosage for my sever back pain following a spinal fusion operation. I have been on the drug for 6 days. I stopped taking percocet # 10 10 days ago, and effexor 7 days ago. My question is, why am I feeling nauseaous, dizzy, and...
by jackie in raleigh, nc, 01/31/2006


by SUNDAY in MOBILE, AK, 04/06/2009

Is there a capsule form of Methadone/Methadose 5 mg. with 5445 imprint ?

I was given a tan/beige capsule imprinted with 5445 and the letter M inside a square.Is this a Methadone/Methadose capsule?If not,what is it???Thank You Very Much.
by Amy in Dayton,Ohio, 12/01/2006

Methadone hydrochloride
Methadone hydrochloride (Dolophine)
Methadone hydrochloride
( METH-ah-dohn)
Pregnancy Category: C Dolophine Methadone HCl Diskets Methadone HCl Intensol Methadose (C-II) (Rx)

Classification: Narcotic analgesic, morphine type

See Also: See also Narcotic Analgesics .

Action/Kinetics: Produces only mild euphoria, which is the reason it is used as a heroin withdrawal substitute and for maintenance programs. Produces physical dependence; withdrawal symptoms develop more slowly and are less intense but more prolonged than those associated with morphine. Does not produce sedation or narcosis. Not effective for preoperative or obstetric anesthesia. Only one-half as potent PO as when given parenterally. Onset: 30-60 min. Peak effects: 30-60 min. Duration: 4-6 hr. t 1/2: 15-30 hr. Both the duration and half-life increase with repeated use due to cumulative effects.

Uses: Severe pain. Detoxification and maintenance of narcotic dependence.

Additional Contraindications: IV use, liver disease, during pregnancy, in children, or in obstetrics (due to long duration of action and chance of respiratory depression in the neonate).

Special Concerns: Use with caution during lactation.

Additional Side Effects: Marked constipation, excessive sweating, pulmonary edema, choreic movements.

Laboratory Test Alterations: Immunoglobulin G.

Drug Interactions: [o]

Additional Drug Interactions: Cimetidine / Respiratory and CNS depression Desipramine / Desipramine blood levels Phenytoin / Methadone effect R/T liver metabolism Protease inhibitors / Respiratory and CNS depression Rifampin / Methadone effect R/T liver metabolism; may precipitate withdrawal

How Supplied: Injection: 10 mg/mL; Oral Concentrate: 10 mg/mL; Oral Solution: 5 mg/5 mL, 10 mg/5 mL; Tablet: 5 mg, 10 mg, 40 mg

?Tablets, Oral Solution, Oral Concentrate, Injection Analgesia.
Adults, individualized: 2.5-10 mg q 3-4 hr, although higher doses may be necessary for severe pain or due to development of tolerance.
Narcotic withdrawal.
Initial: 15-20 mg/day PO (some may require 40 mg/day); then, depending on need of the client, slowly decrease dosage.
Maintenance following narcotic withdrawal.
Adults, individualized, initial: 20-40 mg PO 4-8 hr after heroin is stopped; then, adjust dosage as required up to 120 mg/day.

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