Loteprednol etabonate

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Loteprednol etabonate
Loteprednol etabonate (Alrex, Lotemax)
Loteprednol etabonate
( loh-teh- PRED-nohl)
Pregnancy Category: C Alrex Lotemax (Rx)

Classification: Corticosteroid, ophthalmic

See Also: See also Corticosteroids.

Action/Kinetics: Rapidly metabolized to inactive compounds by eye esterases. After ocular use, minimal amounts are absorbed.

Uses: 0.2% Suspension: Seasonal allergic conjunctivitis. 0.5% Suspension: Steroid-responsive inflammatory conditions of the conjunctiva, cornea, and anterior segment of the globe (e.g., allergic conjunctivitis, superficial punctate keratitis, herpes zoster keratitis, acne rosacea, iritis) cyclitis, certain infective conjunctivitis. Treatment of postoperative inflammation after ocular surgery..

Contraindications: Bacterial, fungal, or viral eye infection.

Special Concerns: Use with caution with cataracts, diabetes mellitus, glaucoma, intraocular hypertension, use beyond 10 days. Safety and efficacy have not been determined in children.

Side Effects: Ophthalmic: Increased IOP, thinning of sclera or cornea, blurred vision, discharge, dry eyes, burning on instillation.

How Supplied: Ophthalmic Suspension: 0.2%, 0.5%

?Suspension, 0.2% Seasonal allergic conjunctivitis.
1 gtt in the affected eye(s) q.i.d.
?Suspension, 0.5% Steroid-responsive disease.
1-2 gtt into the conjunctival sac of the affected eye q.i.d. For the first week, dose may be increased to 1 gtt every hour.
Postoperative inflammation.
1-2 gtt into the conjunctival sac of the operated eye(s) q.i.d. beginning 24 hr after surgery and continuing for 2 weeks.

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