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Haloperidol (Haldol)
(hah-low- PAIR-ih-dohl)
Pregnancy Category: C Apo-Haloperidol Haldol Novo-Peridol Peridol PMS Haloperidol PMS Haloperidol LA (Rx)
Haloperidol decanoate
Haloperidol decanoate (Haldol Decanoate)
(hah-low- PAIR-ih-dohl)
Pregnancy Category: C (decanoate form) Haldol Decanoate 50 and 100 Haldol LA Rho-Haloperidol Decanoate (Rx)
Haloperidol lactate
Haloperidol lactate (Haldol Lactate)
(hah-low- PAIR-ih-dohl)
Pregnancy Category: C Haldol Lactate (Rx)

Classification: Antipsychotic, butyrophenone

Action/Kinetics: Precise mechanism not known. Competitively blocks dopamine receptors in the tuberoinfundibular system to cause sedation. Also causes alpha-adrenergic blockade, decreases release of growth hormone, and increases prolactin release by the pituitary. Causes significant extrapyramidal effects, as well as a low incidence of sedation, anticholinergic effects, and orthostatic hypotension. Narrow margin between the therapeutically effective dose and that causing extrapyramidal symptoms. Also has antiemetic effects. Peak plasma levels: PO, 3-5 hr; IM, 20 min; IM, decanoate: approximately 6 days. Therapeutic serum levels: 3-10 ng/mL. t 1/2, PO: 12-38 hr; IM: 13-36 hr; IM, decanoate: 3 weeks; IV: approximately 14 hr. Plasma protein binding: 90%. Metabolized in liver, slowly excreted in urine and bile.

Uses: Psychotic disorders including manic states, drug-induced psychoses, and schizophrenia. Severe behavior problems in children (those with combative, explosive hyperexcitability not accounted for by immediate provocation). Short-term treatment of hyperactive children who show excessive motor activity with accompanying conduct consisting of impulsivity, poor attention, aggression, mood lability, or poor frustration tolerance. Control of tics and vocal utterances associated with Gilles de la Tourette's syndrome in adults and children. The decanoate is used for prolonged therapy in chronic schizophrenia.
Investigational: Antiemetic for cancer chemotherapy, phencyclidine (PCP) psychosis, intractable hiccoughs, infantile autism. IV for acute psychiatric conditions.

Contraindications: Use with extreme caution, or not at all, in clients with parkinsonism. Lactation.

Special Concerns: PO dosage has not been determined in children less than 3 years of age; IM dosage is not recommended in children. Geriatric clients are more likely to exhibit orthostatic hypotension, anticholinergic effects, sedation, and extrapyramidal side effects (such as parkinsonism and tardive dyskinesia).

Side Effects: Extrapyramidal symptoms, especially akathisia and dystonias, occur more frequently than with the phenothiazines. Overdosage is characterized by severe extrapyramidal reactions, hypotension, or sedation. The drug does not elicit photosensitivity reactions like those of the phenothiazines.

Laboratory Test Alterations: Alkaline phosphatase, bilirubin, serum transaminase; PT (clients on coumarin), serum cholesterol.

Overdose Management: Symptoms: CNS depression, hypertension or hypotension, extrapyramidal symptoms, agitation, restlessness, fever, hypothermia, hyperthermia, seizures, cardiac arrhythmias changes in the ECG, autonomic reactions, coma. Treatment: Treat symptomatically. Antiparkinson drugs, diphenhydramine, or barbiturates can be used to treat extrapyramidal symptoms. Fluid replacement and vasoconstrictors (either norepinephrine or phen-ylephrine) can be used to treat hypotension. Ventricular arrhythmias can be treated with phenytoin. To treat seizures, use pentobarbital or diazepam. A saline cathartic can be used to hasten the excretion of sustained-release products.

Drug Interactions: Amphetamine / Amphetamine effect by uptake of drug at its site of action Anticholinergics / Effect of haloperidol Antidepressants, tricyclic / TCA effects R/T liver breakdown Barbiturates / Effect of haloperidol R/T liver breakdown Guanethidine / Guanethidine effect by uptake of drug at site of action Lithium / Toxicity of haloperidol Methyldopa / Toxicity of haloperidol Phenytoin / Effect of haloperidol due to liver breakdown

How Supplied: Haloperidol: Tablet: 0.5 mg, 1 mg, 2 mg, 5 mg, 10 mg, 20 mg. Haloperidol decanoate: Injection: 50 mg/mL, 100 mg/mL. Haloperidol lactate: Concentrate: 2 mg/mL; Injection: 5 mg/mL ; Solution: 1 mg/mL

?Oral Solution, Tablets Psychoses.
Adults: 0.5-2 mg b.i.d.-t.i.d. up to 3-5 mg b.i.d.-t.i.d. for severe symptoms; maintenance: reduce dosage to lowest effective level. Up to 100 mg/day may be required in some. Geriatric or debilitated clients: 0.5-2 mg b.i.d.-t.i.d. Pediatric, 3-12 years or 15-40 kg: 0.5 mg/day in two to three divided doses; if necessary the daily dose may be increased by 0.5-mg increments q 5-7 days for a total of 0.15 mg/kg/day for psychotic disorders.
Tourette's syndrome.
Adults, initial: 0.5-1.5 mg t.i.d., up to 10 mg daily. Adjust dose carefully to obtain the optimum response. Children, 3 to 12 years: 0.05-0.075 mg/kg/day. Higher doses may be needed for those severely disturbed.
Behavioral disorders/hyperactivity in children.
Children, 3 to 12 years: 0.05-0.075 mg/kg/day. Higher doses may be needed for those severely disturbed.
Intractable hiccoughs (investigational).
1.5 mg t.i.d.
Infantile autism (investigational).
0.5-4 mg/day.
?IM, Lactate Acute psychoses.
Adults and adolescents, initial: 2-5 mg to control acute agitation; may be repeated if necessary q 4-8 hr to a total of 100 mg/day. Switch to PO therapy as soon as possible.
?IM, Decanoate Chronic therapy.
Adults, initial dose: 10-15 times the daily PO dose, not to exceed 100 mg initially, regardless of the previous oral antipsychotic dose; then, repeat q 4 weeks (decanoate is not to be given IV).

Haloperidol Ratings

Overall Rating:



(based on 2 reviews)



Ease of Use:


Overall Satisfaction:





Effectiveness: ****

Ease of Use: **

Overall Satisfaction: ****


Mahaut, Mahaut - 01/13/2014

that he had a client apmoentpint booked very soon and asked if he could call me back in 3 hours' time. I said it was fine, then took myself up to the local medical centre as I felt I shouldn't wait.The GP I saw had never treated me before, though I had seen other doctors on previous occasions there. When he asked what I'd come to see him about, I burst into tears and was unable to articulate myself at all. Eventually I managed to force out I got hit by a patient . He did his best to try to help me elaborate as much as possible, then said he felt I need time off from work, and psychological therapy, and printed off a Work Cover Certificate for 4 weeks. My immediate reaction was I don't think this is a good time of year for me to take time off as a number of staff were on holidays . He then asked if I could think of an alternative course of action, considering I'd been sobbing and rendered mute just moments before when he simply asked the reason for my apmoentpint.Since then the only contact I've had with my workplace i.e. my manager and the HR/Workers Comp representative was when I contacted them that afternoon about the Work Cover Certificate. I was asked to send it in, and they were lovely about it all on the phone, gave me reassurance etc, and asked me if it would be ok if they called me during the time off just to check how I'm going and make sure I'm ok. They also said I could call them if I needed to for any reason at all. It's only a little bit disappointing that they haven't called me it now being Week 4 of my time off. The doctor has given me another certificate for another 4 weeks off so I guess I'll be speaking with them shortly to inform them about that.The insurance company have been very business-like in their approach. It's clear that the person assigned to my claim has little or no knowledge/experience communicating with people who are in psychological distress his manner has been blunt and blase, making an all ready difficult and embarassing situation more of a challenge to deal with, feeding into my paranoia that people would think I was faking it to scam some time off work. The lack of contact from my workplace didn't help in that respect either.Luckily, word must have got around (as it does amongst us nurses) and a few of colleagues have contacted me to check if I was ok and they reassured me thatno one had been suspicious of the authenticity of my trauma and that everyone was missing me at work. Their kind words helped minimise my paranoia and embarassment.I received a letter from the insurer with the name and address of a clinical psychologist, and the date and time of an apmoentpint they made with him on my behalf that I was to attend so that she could conduct an evaluation of my illness and an assess the level of liability of my workplace in relation to it. At the end of the apmoentpint she made it clear that she would be surprised if the insurer rejected my claim.I've commenced regular sessions with a shrink and whilst it's very early days (in that I still haven't been able to articulate the incident and am having regular panic attacks etc) I think I'll be ok though both doctors have doubted whether I could or should return to the mental health sector due to the unpredictable nature of the patients' behaviour. From those comments I'm thinking I shouldn't return to nursing in any way at all as every patient is an unknown quantity whether they're in a medical, surgical or mental health ward. And assaults of nurses by patients occurs in every hospital, with a high enough frequency to prompt the whole Zero Tolerance Policy. The NSW Health is a zero tolerance zone posters that are displayed prominently in every ward are there because nurses are attacked by patients not just mental health patients.So I'll see how it plays out. The insurer hasn't contacted me since my apmoentpint with their psychologist two weeks ago, so I'm presuming my benefits will continue until the end of the next Work Cover Certificate at least. But it does feel like you are kind of left in the dark by the people who have all the information about you, your illness, and about the workers compensation process. I requested a copy of the insurer appointed psychologist and was emailed a form to fill out, instructing me of a $30 fee required for the privilege of getting a copy of information about myself.Each day off when I wake up I feel like you do when you wake up ill but are tossing up whether you are ill enough to call in sick, and if you are ill enough you wonder whether you sound ill enough when you call up, blah blah blah. The thought of being off work for another month is daunting because this is not a holiday if I could feel well and be back at work tomorrow without any trepidation, I'd be there in a flash. Spending day after day with little to do but feel anxious, bored, purposeless and stupid is exhausting compared to a 10 hour nightshift. You spend a lot of time dealing with the uncertainty of when you'll be back at work, and where, with the constant worry that the moment could come at any time whereby the insurer deems it appropriate to cease the benefits. You feel at the mercy of an unfamiliar, profit-driven corporation not your employer and that you're deliberately given minimal information about the process. Don't get me wrong I received the Work Cover pamphlets etc, but have had to do some research on the internet myself to get a better understanding (which led me to this page).No system is perfect, but given the nature of our work as care providers you would think a little empathy and consideration could be shown to us when we need a little care ourselves. The system seems to be flawed in regards to having to deal with an insurance body. Perhaps the responsibility of assessing claims can't be left with say the HR department or a Staff Health team because the assessment needs to be done by an third party if only to ensure an unbiased view. However, considering I've heard similar stories to mine where you feel like the insurer doubts you from the get-go and is on the lookout for reasons against approving your claim, it would seem the independent third party is biased anyway.