Fluvastatin sodium

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Fluvastatin sodium
Fluvastatin sodium (Lescol)
Fluvastatin sodium
(flu-vah- STAH-tin)
Pregnancy Category: X Lescol (Rx)

Classification: Antihyperlipidemic agent

See Also: See also Antihyperlipidemic Agents--HMG-CoA Reductase Inhibitors .

Action/Kinetics: t 1/2: 1.2 hr. Undergoes extensive first-pass metabolism. Significantly bound (greater than 98%) to plasma protein. Metabolized in the liver with 90% excreted through the feces and 5% through the urine.

Uses: Adjunct to diet for the reduction of elevated total and LDL cholesterol levels in clients with primary hypercholesterolemia (type IIa and IIb) whose response to diet and other nondrug measures have been inadequate. The lipid-lowering effects of fluvastatin are enhanced when it is combined with a bile-acid binding resin or with niacin. Reduce triglycerides and apolipoprotein B in primary hypercholesterolemia and mixed dyslipidemia. To slow the progression of coronary atherosclerosis in coronary heart disease.

Special Concerns: Use with caution in clients with severe renal impairment.

Side Effects: Side effects listed are those most common with fluvastatin. A complete list of possible side effects is provided under Antihyperlipidemic Agents--HMG-CoA Reductase Inhibitors. GI: N&V, diarrhea, abdominal pain or cramps, constipation, flatulence, dyspepsia, tooth disorder. Musculoskeletal: Myalgia, back pain, arthralgia, arthritis. CNS: Headache, dizziness, insomnia. Respiratory: URI, rhinitis, cough, pharyngitis, sinusitis. Miscellaneous: Rash, pruritus, fatigue, influenza, allergy, accidental trauma.

Laboratory Test Alterations: Serum transaminases.

Drug Interactions: [.]

Additional Drug Interactions: Alcohol / Fluvastatin absorbed Digoxin / Bioavailability of fluvastatin Rifampin / Fluvastatin clearance

How Supplied: Capsule: 20 mg, 40 mg

?Capsules Treat primary hypercholesterolemia. Antihyperlipidemic to slow progression of coronary atherosclerosis.
Adults, initial: 20-40 mg once daily at bedtime. Dose range: 20-80 mg/day. Splitting the 80-mg dose into a twice-daily regimen results in a modest improvement in LDL cholesterol.

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Fluvastatin sodium

Effectiveness: **

Ease of Use: *****

Overall Satisfaction: **


Sergey, Sergey - 01/13/2014

High blood pressure IS an uniedlyrng health condition. While it is possible to lose weight if you consume less calories than your body burns off, a diet consisting of only frozen meals is not a healthy way to go about it. Plus, the majority of people will fall of the diet and start binge eating. Look at it this way, if someone already have than much self-discipline and will power to make themselves eat low calorie, they would not be obese in the first place.Your friend should eat fresh vegetables, fruits, and lean meat. She should avoid refined sugar, bleached flour, and foods containing hydrogenated oil. She should also cut back on salt because too much salt will only make her high blood pressure worse. She should, even with bad knees, go for daily walkings because at 350 lbs she is NOT going to lose enough weight quick enough to help he since she is in her 40 s and the clock is ticking. At her age, when she is that overweight coupled with high blood pressure, the chances of developing serious health problems such as heart disease, stroke, and diabetes increases dramatically. She does not have much time, so she needs to burn the candles at both ends to lose the fat.