Flavoxate hydrochloride

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Flavoxate hydrochloride
Flavoxate hydrochloride (Urispas)
Flavoxate hydrochloride
(flay- VOX-ayt)
Pregnancy Category: B Urispas (Rx)

Classification: Urinary tract antispasmodic

Action/Kinetics: Relieves muscle spasms of the urinary tract by relaxing the detrusor muscle by cholinergic blockade and also by a direct effect. Also has local anesthetic and analgesic effects. Well absorbed from GI tract; 10%-30% is excreted in urine.

Uses: Symptomatic relief of urinary tract irritation, dysuria, urgency, nocturia, suprapubic pain, incontinence associated with cystitis, prostatitis, urethritis, urethrocystitis, and other urinary tract disorders. Compatible for use with urinary tract germicides.

Contraindications: Obstructive disorders of urinary tract, including pyloric or duodenal obstructions, obstructive intestinal lesions, ileus, achalasia, obstructive uropathies of the lower urinary tract, and GI hemorrhage.

Special Concerns: Use with caution in glaucoma and during lactation. Confusion is more likely to occur in geriatric clients. Safety and effectiveness have not been determined in children less than 12 years of age.

Side Effects: GI: N&V, xerostomia. CNS: Drowsiness, headache, vertigo, nervousness, mental confusion (especially in the elderly). CV: Tachycardia, palpitations. Hematologic: Eosinophilia, leukopenia. Ophthalmologic: Blurred vision, increased ocular tension, accommodation disturbances. Other: Urticaria and other dermatoses, fever, dysuria.

How Supplied: Tablet: 100 mg

Adults and children over 12 years: 100 or 200 mg t.i.d.-q.i.d. Reduce dose when symptoms improve.

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