Questions | Reviews

Can Etomidate be safely administered in an 8month pregnant pt needing emergent RSI?

Flight Crew responded to call necessitating the emergent intubation of a woman who was 8 month pregnant in need of a definitive airway for survival. The quetion is: can etomidate be safely administered in an 8month pregnant pt needing emergent RSI? wh...
by Alex Markwell in Florida, 05/05/2006

Is etomidate FDA approved for use in pediatric RSI

I am looking for information on the FDA approval of etomidate in pediatric RSI?
by karen south in Kalispell, MT, 11/09/2006

Adrenal supression

Can the administration of standard pre intubation doses of etomidate cause further adrenal suppresion in septic patients of which up to one third have a relative addrenal insuffiency?
by M. Wooley, m.d. in San Anyonio, Texas, 05/13/2006

what are effects of giving etomidate subq

Got a call from the ER doc in the hospital wanting to know what effects to expect/manifest upon giving etomidate subcutaneously instead of IV. no info given on pt particulars i.e. (did accident happen in ER or is this why the pt is here?) Any help wou...
by Craig Mayberry, Rph in Ft Worth Texas, 02/27/2009

suicide and etomidate

I was watching a show on the Discovery channel called 48 HRS Hard Evidence. The story was about a woman who was an RN, who had an affair with a married surgeon. He eventually left his wife and he and the RN married. He was sick he had diabetes and a f...
by Susan in Roebling,NJ, 04/14/2006

Etomidate (Amidate)
(eh- TOM-ih-dayt)
Pregnancy Category: C Amidate (Rx)

Classification: General anesthetic and adjunct to general anesthesia

Action/Kinetics: Is a hypnotic with no analgesic activity. Appears to act like GABA and is thought to exert its mechanism by depressing the activity of the brain stem reticular system. Minimal CV and respiratory depressant effects. Onset: 1 min. Duration: 3-5 min. t 1/2: 75 min. Rapidly metabolized in the liver with inactive metabolites excreted mainly through the urine.

Uses: Induction of general anesthesia. As a supplement to nitrous oxide during short surgical procedures. Investigational: Prolonged sedation of critically ill or ventilator-dependent clients (is an increased risk of acute insufficiency and mortality).

Special Concerns: Use with caution during lactation. Safety and efficacy have not been established in children less than 10 years of age.

Side Effects: Skeletal muscle: Myoclonic skeletal muscle movements, tonic movements. Respiratory: Apnea of short duration, hyperventilation or hypoventilation, laryngospasm. CV: Either hypertension or hypotension; tachycardia or bradycardia; arrhythmias. GI: Postoperative N&V. Miscellaneous: Eye movements, averting movements, hiccoughs, snoring.

How Supplied: Injection: 2 mg/mL

?IV Only Induction of anesthesia.
Adults and children over 10 years of age: 0.2-0.6 mg/kg (usual: 0.3 mg/kg) injected over 30-60 sec.

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