Doxepin hydrochloride


Questions | Reviews

TIME FOR ARRIVING FIRST RESPONDS


I HAVE A N CHORONIC ENXIETY AND CHORONIC DEPRESS. I HAVE STARTED NEARLY 10 DAYS THIS DRUG. HOW MANY TIME DO U THINK I CAN ENJOY OF MY LIFE .IM SUFFERING ALOT.I EVEN CAN ADHONIA ALWAYS WAS A SHADOW IN MY LIFE
by BABAK in TEHRAN -IRAN, 04/05/2006

Doxepin hydrochloride
Doxepin hydrochloride (Adapin, Sinequan)
Doxepin hydrochloride
( DOX-eh-pin)
Pregnancy Category: C Alti-Doxepin Apo-Doxepin Novo-Doxepin Rho-Doxepin Sinequan Triadapin Zonalon (Rx)

Classification: Antidepressant, tricyclic

See Also: See also Antidepressants, Tricyclic .

Action/Kinetics: Metabolized to the active metabolite, desmethyldoxepin. Moderate anticholinergic effects and orthostatic hypotension; high sedative effects. Therapeutic plasma levels of both doxepin and desmethyldoxepin: 100-200 ng/mL. Time to reach steady state: 2-8 days. t 1/2: 8-24 hr.

Uses: Psychoneurotic clients with depression or anxiety. Depression or anxiety due to organic disease or alcoholism. Psychotic depressive disorders with associated anxiety, including involutional depression and manic-depressive disorders. Depression or anxiety associated with organic disease. PUD. Dermatologic disorders including chronic urticaria, angioedema, and nocturnal pruritus due to atopic eczema.

Contraindications: Use in children less than 12 years of age. Glaucoma or a tendency for urinary retention.

Special Concerns: Safety has not been determined in pregnancy.

Additional Side Effects: Doxepin has a high incidence of side effects, including a high degree of sedation, decreased libido, extrapyramidal symptoms, dermatitis, pruritus, fatigue, weight gain, edema, paresthesia, breast engorgement, insomnia, tremor, chills, tinnitus, and photophobia.

How Supplied: Capsule: 10 mg, 25 mg, 50 mg, 75 mg, 100 mg, 150 mg; Concentrate: 10 mg/mL; Cream: 5%

Dosage
?Capsules, Oral Concentrate Antidepressant, mild to moderate anxiety or depression.
Adults, initial: 25 mg t.i.d. (or up to 150 mg can be given at bedtime); then, adjust dosage to individual response (usual optimum dosage: 75-150 mg/day). Geriatric clients, initially: 25-50 mg/day; dose can be increased as needed and tolerated.
Severe symptoms.
Initial: 50 mg t.i.d.; then, gradually increase to 300 mg/day.
Emotional symptoms with organic disease.
25-50 mg/day.
Antipruritic.
10-30 mg at bedtime.
?Cream 5%
Apply a thin film q.i.d. with at least a 3-4 hr interval between applications.

Doxepin hydrochloride Ratings

Overall Rating:

0.0

 

(based on 0 reviews)

Effectiveness:

Ease of Use:

Overall Satisfaction:

Reviewit

Reviews

Sure is quiet in here. You can write the first review of Doxepin hydrochloride.