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Dexamethasone sodium phosphate Dosage, Interactions, Side Effects, How to Use

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Pregnancy and Iontophoresis with dexamethasone  Is dexamethasone administered via iontophoresis safe when used during pregnacy, away from the trunk?  Such as the knee? Thank you in advance for your reply. by Donna Anderson, 11/05/2006

Dexamethasone Sodium Phosphate Pain Patch I am being administered this drug by way of a pain patch to reduce inflamation around a tendon in my upper arm area. Should I have any side effects with 9 doses administered for the completion of the session? by Patricia E in NC, 05/02/2006

Is Dexamethasone sodium phosphate safe for patients with Osteonecrosis? I have recently had bi-lateral Total Hip Replacements due to Osteonecrosis of both femoral heads. I am now doing physical therapy. My knee has started giving me terrible problems and the therapist has started using 1% Dexamethasone Sodium Phosphate vi... by Chris B in Oregon, USA, 11/23/2005

Iontophoresis and Dexamethesone My husband has severe osteoarthritis. Due to several circumstances, he cannot have knee replacements at this time. Oral non-steroidal drugs have not helped him. I belive he has tried them all .When he was taking physical therapy, they applied an iont... by Marianna R in Indiana , PA, 11/16/2005

Dexamethasone sodium phosphate
Dexamethasone sodium phosphate (Decadron Phosphate)
Dexamethasone sodium phosphate
(dex-ah- METH-ah-zohn) Systemic: Dalalone Decadron Phosphate Decaject Dexasone Dexone Hexadrol Phosphate R.O.-Dexone Solurex (Rx). Inhaler: Decadron Phosphate Respihaler (Rx). Nasal: Decadron Phosphate Turbinaire (Rx). Ophthalmic: AK-Dex Decadron Phosphate Ophthalmic Diodex PMS-Dexamethasone Sodium Phosphate Spersadex (Rx). Otic: AK-Dex Decadron I-Methasone (Rx). Topical: Decadron Phosphate (Rx)

Classification: Glucocorticoid, synthetic

See Also: See also Corticosteroids .

Action/Kinetics: Rapid onset and short duration of action.

Additional Uses For IV or IM use in emergency situations when dexamethasone cannot be given PO. Intranasally for nasal polyps, allergic or inflammatory nasal conditions.

Contraindications: Acute infections, persistent positive sputum cultures of Candida albicans. Lactation.

Special Concerns: Use during pregnancy only if benefits outweigh risks.

Side Effects: Following inhalation: Nasal and nasopharyngeal irritation, burning, dryness, stinging, headache.

How Supplied: Metered dose inhaler 0.1 mg/inh; Injection: 4 mg/mL, 10 mg/mL, 24 mg/mL; Ophthalmic ointment: 0.05%; Ophthalmic solution: 0.1%

Dosage
?IM, IV Most uses.
Range: 0.5-9 mg/day ( 1/3- 1/2 the PO dose q 12 hr).
Cerebral edema.
Adults, initial: 10 mg IV; then, 4 mg IM q 6 hr until maximum effect obtained (usually within 12-24 hr). Switch to PO therapy (1-3 mg t.i.d.) as soon as feasible and then slowly withdraw over 5-7 days.
Shock, unresponsive.
Initial: either 1-6 mg/kg IV or 40 mg IV; then, repeat IV dose q 2-6 hr as long as necessary.
?Intralesional, Intra-articular, Soft Tissue Injections
0.4-6 mg, depending on the site (e.g., small joints: 0.8-1 mg; large joints: 2-4 mg; soft tissue infiltration: 2-6 mg; ganglia: 1-2 mg; bursae: 2-3 mg; tendon sheaths: 0.4-1 mg.
?Metered Dose Inhaler Bronchial asthma.
Adults, initial: 3 inhalations (84 mcg dexamethasone/inhalation) t.i.d.-q.i.d.; maximum: 3 inhalations/dose; 12 inhalations/day. Pediatric: initial, 2 inhalations t.i.d.-q.i.d.; maximum: 2 inhalations/dose; 8 inhalations/day.
?Intranasal Allergies, nasal polyps.
Adults: 2 sprays (total of 168 mcg dexamethasone) in each nostril b.i.d.-t.i.d. (maximum: 12 sprays/day); pediatric, 6-12 years: 1-2 sprays (total of 84-168 mcg dexamethasone) in each nostril b.i.d. (maximum: 8 sprays/day).
?Ophthalmic Ointment
Instill a small amount of the ointment into the conjunctival sac t.i.d.-q.i.d. As response is obtained, reduce the number of applications.
?Ophthalmic Solution
Initial: Instill 1-2 gtt into the conjunctival sac q hr during the day and q 2 hr at night until response obtained. After a favorable response reduce to 1 gtt q 4 hr and later 1 gtt t.i.d.-q.i.d.
?Otic Solution
3-4 gtt into the ear canal b.i.d.-t.i.d.
?Topical Cream
Apply sparingly to affected areas and rub in.