Dexamethasone


Questions | Reviews

dexamethasone dosage for guttural pouch


Could you please tell me the dosage and the length of time to administer dexamethasone for my horse? I have given him 15 grams for the past 3 days and have noticed a great overall improvement. How many more days should I treat and should I decrease th...
by denise in R.I., 07/24/2006

Safely going off Dexamethasone


I have been taking a 4MG dose three times a day at meal times of Dexamethasone for the past two weeks while undergoing whole brain radiation to eliminate 6 renal cell carcenoma tumors resulting from my stage four Renal Cancer. I only have three more d...
by Karl J in Ogden, Utah, 01/13/2006

Water retention


I take 1.5 mg of Dexamethasone every day. I have gained weight quickly i.e. 9 pds. in 6 -8 weeks. The first 5 pounds was real fast like in just a few weeks (2-3), then it slowed down a bit but I kept gaining every week. I feel very bloated. I went on ...
by Liz in U.S.A., 06/03/2006

Effects of going off high dosages of dexamethasone


My husband was diagnosed with multiple myeloma in Jan. 2006 and was put on thalimid and dexamethasone. He would take 40mgs of Dexamethasone for four days and then he would stop for four days. He is now in remission and his onocoligist took him off of ...
by Billie Smith in Battle Creek, Michigan, 05/14/2006

Dexamethasone contraindications


Dexamethasone should be used in caution in patients with which of the following conditions? A. Hypotension, diabetes and cirrhosis B. Cirrhosis, hypothyroidism and hypertension C Herpes zoster, acne and localized skin infection
by Diane in Tacoma, WA 98446, 04/26/2006

Dexamethasone
Dexamethasone (Decadron)
Dexamethasone
(dex-ah- METH-ah-zohn) Oral: Decadron Dexameth Dexamethasone Intensol Dexasone Dexone Hexadrol (Rx). Topical: Aeroseb-Dex Decaderm (Rx). Ophthalmic: Maxidex Ophthalmic (Rx)

Classification: Glucocorticoid, synthetic

See Also: See also Corticosteroids .

Action/Kinetics: Long-acting. Low degree of sodium and water retention. Diuresis may ensue when transferred from other corticosteroids to dexamethasone. t 1/2: 110-210 min.

Additional Uses In acute allergic disorders, PO dexamethasone may be combined with dexamethasone sodium phosphate injection and used for 6 days. To test for adrenal cortical hyperfunction. Cerebral edema due to brain tumor, craniotomy, or head injury. Investigational: Diagnosis of depression. Antiemetic in cisplatin-induced vomiting. Prophylaxis or treatment of acute mountain sickness. Decrease hearing loss in bacterial meningitis. Bronchopulmonary dysplasia in preterm infants. Hirsutism.

Contraindications: Use for replacement therapy in adrenal cortical insufficiency.

Special Concerns: Use during pregnancy only if benefits outweigh risks.

Additional Drug Interactions: Ephedrine effect of dexamethasone R/T liver breakdown.

How Supplied: Concentrate: 1 mg/mL; Elixir: 0.5 mg/5 mL; Ophthalmic suspension: 0.1%; Tablet: 0.25 mg, 0.5 mg, 0.75 mg, 1 mg, 1.5 mg, 2 mg, 4 mg, 6 mg

Dosage
?Oral Concentrate Tablets, Elixir Most uses.
Initial: 0.75-9 mg/day; maintenance: gradually reduce to minimum effective dose (0.5-3 mg/day).
Suppression test for Cushing's syndrome.
0.5 mg q 6 hr for 2 days for 24-hr urine collection (or 1 mg at 11 p.m. with blood withdrawn at 8 a.m. for blood cortisol determination).
Suppression test to determine cause of pituitary ACTH excess.
2 mg q 6 hr for 2 days (for 24-hr urine collection).
Acute allergic disorders or acute worsening of chronic allergic disorders.
Day 1: Dexamethasone sodium phosphate injection, 4-8 mg IM. Days 2 and 3: Two 0.75-mg dexamethasone tablets b.i.d. Day 4: One 0.75-mg dexamethasone tablet b.i.d. Days 5 and 6: One 0.75-mg dexamethasone tablet. Day 7: No treatment. Day 8: Follow-up visit to physician.
?Topical Aerosol, Cream
Apply sparingly as a light film to affected area b.i.d.-t.i.d.
?Ophthalmic Suspension
1-2 gtt in the conjunctival sac q hr during day and q 2 hr during night until a satisfactory response obtained; then, 1 gtt q 4 hr and finally 1 gtt q 6-8 hr.

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