Questions | Reviews
My daughter has to have an eeg in early april (dr. heard a heart murmur). She will be 7 1/2 weeks old. She needs to be sedated for the procedure and they are going to use chloral hydrate. Are there any side effects or things I should be worried about....
by Bob in Fairview, NJ, 03/22/2007
Classification: Nonbenzodiazepine, nonbarbiturate sedative-hypnotic
Action/Kinetics: Metabolized to trichloroethanol, which is the active metabolite causing CNS depression. Produces only slight hangover effects and is said not to affect REM sleep. High doses lead to severe CNS depression, as well as depression of respiratory and vasomotor centers (hypotension). Both psychologic and physical dependence develop. Onset: Within 30 min. Duration: 4-8 hr. t 1/2, trichloroethanol: 7-10 hr. Readily absorbed from the GI tract and distributed to all tissues; passes the placental barrier and appears in breast milk. Metabolites excreted by kidney.
Uses: Short-term hypnotic. Daytime sedative and sedation prior to EEG procedures. Preoperative sedative and postoperative as adjunct to analgesics. Prevent or reduce symptoms of alcohol withdrawal.
Contraindications: Marked hepatic or renal impairment, severe cardiac disease, lactation. PO use in clients with esophagitis, gastritis, or gastric or duodenal ulcer.
Special Concerns: Use by nursing mothers may cause sedation in the infant. Dose decrease may be necessary in geriatric clients due to age-related decrease in both hepatic and renal function.
CNS: Paradoxical paranoid reactions. Sudden withdrawal in dependent clients may result in
Sudden intolerance to the drug following prolonged use may result in respiratory depression, hypotension, cardiac effects, and possibly death.
GI: N&V, diarrhea, bad taste in mouth, gastritis, increased peristalsis.
GU: Renal damage, decreased urine flow and uric acid excretion.
Miscellaneous: Skin reactions, hepatic damage, allergic reactions, leukopenia, eosinophilia.
Laboratory Test Alterations: 17-Hydroxycorticosteroids. Interference with fluorescence tests for catecholamines and copper sulfate test for glucose.
How Supplied: Capsule: 500 mg; Suppository: 325 mg, 500 mg, 650 mg; Syrup: 500 mg/5 mL