Carteolol hydrochloride

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Carteolol hydrochloride
Carteolol hydrochloride (Cartrol)
Carteolol hydrochloride
(kar- TEE-oh-lohl)
Pregnancy Category: C Cartrol Ocupress (Rx)

Classification: Beta-adrenergic blocking agent

See Also: See also Beta-Adrenergic Blocking Agents .

Action/Kinetics: Has both beta-1 and beta-2 receptor blocking activity. It has no membrane-stabilizing activity but does have moderate intrinsic sympathomimetic effects. Low lipid solubility. t 1/2: 6 hr. Duration, ophthalmic use: 12 hr. Approximately 50%-70% excreted unchanged in the urine.

Uses: PO. Hypertension. Investigational: Reduce frequency of anginal attacks. Ophthalmic. Alone or with other drugs to lower IOP in chronic open-angle glaucoma and intraocular hypertension.

Contraindications: Severe, persistent bradycardia. Bronchial asthma or bronchospasm, including severe COPD.

Special Concerns: Dosage not established in children.

Additional Side Effects: Ophthalmic use. Transient irritation, burning, tearing, conjunctival hyperemia, edema, blurred or cloudy vision, photophobia, decreased night vision, ptosis, blepharoconjunctivitis, abnormal corneal staining, corneal sensitivity.

How Supplied: Ophthalmic solution: 1%; Tablet: 2.5 mg, 5 mg

?Tablets Hypertension.
Initial: 2.5 mg once daily either alone or with a diuretic. If response is inadequate, the dose may be increased gradually to 5 mg and then 10 mg/day as a single dose. Maintenance: 2.5-5 mg once daily. Doses greater than 10 mg/day are not likely to increase the beneficial effect and may decrease the response. Increase the dosage interval in clients with renal impairment.
Reduce frequency of anginal attacks.
10 mg/day.
?Ophthalmic Solution
Usual: 1 gtt in affected eye b.i.d. If the response is unsatisfactory, concomitant therapy may be initiated.

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