Bisoprolol fumarate

Questions | Reviews ***~

Weight gain when taking Bisoprolol (10 - 12.5 mg daily)

I was first prescribed Bisoprolol in November 2005, starting with a daily dose of 2.5 mg. Since then the dose has progressively been increased to the present level of 10 to 12.5 mg in December 2006. I have put on 35 lbs since I started taking this dru...
by J.A. in Solihull, England, 04/02/2007


I am taking Bisopropol with Digoxin for aterial fibrillation. This was prescribed by my doctor. Is it safe to take these two medications alongside each other
by Ian McDade in Bristol England, 01/03/2009

Bisoprolol fumarate
Bisoprolol fumarate (Zebeta)
Bisoprolol fumarate
( BUY-soh- proh-lol)
Pregnancy Category: C Zebeta (Rx)

Classification: Beta-adrenergic blocking agent

See Also: See also Beta-Adrenergic Blocking Agents .

Action/Kinetics: Inhibits beta-1-adrenergic receptors and, at higher doses, beta-2 receptors. No intrinsic sympathomimetic activity and no membrane-stabilizing activity. t 1/2: 9-12 hr. Over 90% of PO dose is absorbed. Approximately 50% is excreted unchanged through the urine and the remainder as inactive metabolites; a small amount (less than 2%) is excreted through the feces.

Uses: Hypertension alone or in combination with other antihypertensive agents. Investigational: Angina pectoris, SVTs, PVCs.

Special Concerns: Use with caution during lactation. Safety and efficacy have not been determined in children. Since bisoprolol is selective for beta-1 receptors, it may be used with caution in clients with bronchospastic disease who do not respond to, or who cannot tolerate, other antihypertensive therapy.

Laboratory Test Alterations: AST, ALT, uric acid, creatinine, BUN, serum potassium, glucose, and phosphorus. WBCs and platelets.

How Supplied: Tablet: 5 mg, 10 mg

?Tablets Antihypertensive.
Dose must be individualized. Adults, initial: 5 mg once daily (in some clients, 2.5 mg/day may be appropriate). Maintenance: If the 5-mg dose is inadequate, the dose may be increased to 10 mg/day and then, if needed, to 20 mg once daily. In clients with impaired renal or hepatic function, the initial daily dose should be 2.5 mg with caution used in titrating the dose upward.

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