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Jul 13, 2005, 7:37 PM
Post #3 of 15
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Hey Guest, how are you doing? Ask your Doctor about steroid therapy. Steroid therapy has been implicated in the development of vasculitis (inflammation of a blood or lymph vessel); however, vasculitis is seen in patients who have never recieved steroids. Nail-fold thrombi, small infarcts on the volar surface of the hands, digital gangrene, and ulcers of the lower part of the legand the ankle are manifestations of rheumatoid vasculitis. Both sensory and motor types of neuropathy result from vasculitis of the vasa nervorum. Vasculitis of the cranial, coronary, and mesenteric vessels has been observed. In patients where infections may be a serious complication wih marked neutropenia (leukopenia in which the decrease in white blood cells is chiefly in neutrophils), splenectomy may improve the neutropenia. Neutropenia, however, may recur after splenectomy. The course of the arthritis is not affected by splenectomy. The Food and Drug Administration (FDA) has granted approval to Mylan Technologies, Inc., for the first generic version of Alza Corporation's Duragesic Patch (Fentanyl Transdermal System) used to treat patients suffering from severe chronic pain that cannot be managed with alternative analgesics. When applied to the skin, this patch technology delivers fentanyl, an opioid pain medication that is slowly absorbed into the body through the skin providing pain relief for up to three days (72 hours). REFERENCES The Food and Drug Administration (FDA): FDA Clears the way for Generic Versions of Transdermal Patches to Treat Chronic Pain Bruce C. Gilliland Mart Mannik: RHEUMATOID ARTHRITIS; CLINICAL MANIFESTATIONS Harrison's Principles of Internal Medicine, Eighth Edition; chap. 359, p250-3. Complementary Medical Association: VARICOSE VEINS PRO-SERO Patch Inc.: Usage Best wishes,
(This post was edited by bgilley on Aug 22, 2005, 1:34 PM)
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