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Oxycodone and acetaminophen
Oxycodone and Acetaminophen (Endocet, Roxicet)
Oxycodone and acetaminophen
(ox-ee-KOH-dohn, ah-SEAT-ah-MIN-oh-fen)
Pregnancy Category: C
Endocet
Oxycocet
Percocet
Percocet 2.5/325, 5/325, and 7.5/500
Percocet-Demi
Roxicet
(C-II) (Rx)
Classification:
Analgesic
See Also:
See also Acetaminophen and Narcotic Analgesics.
Content:
Endocet and Roxicet Tablets: Narcotic analgesic: Oxycodone hydrochloride, 5 mg. Analgesic: Acetaminophen, 325 mg. Percocet Tablets 2.5/325: Oxycodone hydrochloride, 2.5 mg and Acetaminophen, 325 mg; Percocet Tablets 5/325: Oxycodone hydrochloride, 5 mg and Acetaminophen, 325 mg; Percocet Tablets 7.5/500: Oxycodone hydrochloride, 7.5 mg and Acetaminophen, 500 mg. Roxicet Oral Solution: Oxycodone hydrochloride, 5 mg/5 mL and Acetaminophen, 325 mg/5 mL.
Uses:
Relief of moderate to moderately severe pain.
Contraindications:
Hypersensitivity to either oxycodone or acetaminophen.
Special Concerns:
Can produce drug dependence and has abuse potential. The respiratory depressant effects of oxycodone can be exaggerated in clients with head injury, other intracranial lesions, or a preexisting increase in intracranial pressure. Use with caution in clients who are elderly, are debilitated, have severely impaired hepatic or renal function, are hyperthyroid, have Addison's disease, have prostatic hypertrophy, or have urethral stricture. Use for acute abdominal conditions may obscure the diagnosis or clinical course. Use with caution during lactation. Safety and efficacy in children have not been established.
Side Effects:
Commonly, dizziness, lightheadedness, N&V;, and sedation; these effects are more common in ambulatory clients than nonambulatory clients. Other side effects include euphoria, dysphoria, constipation, skin rash, and pruritus. See also individual components.
Drug Interactions:
- Anticholinergic drugs / Production of paralytic ileus
- Antidepressants, tricyclic /
 Effect of either the TCAs or oxycodone
- CNS depressants (including other narcotic analgesics, phenothiazines, antianxiety drugs, sedative-hypnotics, anesthetics, alcohol) / Additive CNS depression
- MAO inhibitors / Effect of either the MAO inhibitor or oxycodone
How Supplied:
See Content
Dosage
•Oral Solution, Tablets
Analgesic.
Adults: 5 mL of the oral solution q 6 hr or 1 tablet q 6 hr as needed for pain. |
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