[.
]Action/Kinetics:
Absorbed more slowly than most benzodiazepines. Peak plasma levels: 2-4 hr. t1/2: 5-20 hr. Broken down in the liver to inactive metabolites, which are excreted through both the urine and feces. Reputed to cause less drowsiness than chlordiazepoxide.
Uses:
Anxiety, tension, anxiety with depression. Adjunct in acute alcohol withdrawal.
Special Concerns:
Dosage has not been established in children less than 12 years of age; use is not recommended in children less than 6 years of age.
Additional Side Effects:
Paradoxical reactions characterized by sleep disorders and hyperexcitability during first weeks of therapy. Hypotension after parenteral administration.
How Supplied:
Capsule: 10 mg, 15 mg, 30 mg; Tablet: 15 mg
Dosage
•Capsules, Tablets
Anxiety, mild to moderate.
Adults: 10-30 mg t.i.d.-q.i.d.
Anxiety, tension, irritability, agitation.
Geriatric and debilitated clients: 10 mg t.i.d.; can be increased to 15 mg t.i.d.-q.i.d.
Alcohol withdrawal.
Adults: 15-30 mg t.i.d.-q.i.d.
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