Pyrantel pamoate


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Longevity of Treatment with Pyrantel Pelmoate by Doreen from USA 12/30/2006

Side effects of Pyrantel if overdose by angelia from tennessee 07/22/2006

Using this product on puppy five weeks old by Barry Ashbrook from Montpelier, Va. 04/09/2006

Pyrantel Pamoate and pinworms by Kelly from New Orleans, LA 02/06/2006

Allergic reaction to pyrantel pamoate by Kennette Day from Richardson, TX 11/26/2005

Pyrantel pamoate
Pyrantel pamoate (Antiminth)
Pyrantel pamoate
(pie- RAN-tell)
Pregnancy Category: C Antiminth Combantrin Pin-Rid Pin-X Reese's Pinworm (OTC)

Classification: Anthelmintic

Action/Kinetics: Has neuromuscular blocking effect which paralyzes the helminth, allowing it to be expelled through the feces. Also inhibits cholinesterases. Poorly absorbed from GI tract. Peak plasma levels: 0.05-0.13 mcg/mL after 1-3 hr. Partially metabolized in liver. Fifty percent is excreted unchanged in feces and less than 15% excreted unchanged in urine.

Uses: Pinworm (enterobiasis) and roundworm (ascariasis) infestations. Multiple helminth infections, as it is also effective against roundworm and hookworm.

Contraindications: Pregnancy. Hepatic disease.

Special Concerns: Use with caution in presence of liver dysfunction. Safe use in children less than 2 years of age has not been established.

Side Effects: GI (most frequent): Anorexia, N&V, abdominal cramps, diarrhea. Hepatic: Transient elevation of AST. CNS: Headache, dizziness, drowsiness, insomnia. Miscellaneous: Skin rashes.

Drug Interactions: Use with piperazine for ascariasis results in antagonism of the effect of both drugs.

How Supplied: Suspension: 144 mg/30 mL, 720 mg/5 mL; Tablet: 180 mg

Dosage
?Liquid Oral Suspension, Tablets
Adults and children: One dose of 11 mg/kg (maximum). Maximum total dose: 1.0 g.