Nortriptyline hydrochloride
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Nortriptyline hydrochloride Questions
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Nortriptyline hydrochloride
Nortriptyline hydrochloride (Aventyl)
Nortriptyline hydrochloride
(nor-
TRIP-tih-leen)
Pregnancy Category: C
Apo-Nortriptyline
Aventyl
Gen-Nortriptyline
Norventyl
Novo-Nortriptyline
Nu-Nortriptyline
PMS-Nortriptyline
Pamelor
(Rx)
Classification:
Antidepressant, tricyclic
See Also:
See also
Antidepressants, Tricyclic
[.
]
Action/Kinetics:
Manifests moderate anticholinergic and sedative effects but slight orthostatic hypotensive effects.
Effective plasma levels: 50-150 ng/mL.
t
1/2: 18-44 hr.
Time to reach steady state: 4-19 days.
Uses:
Treatment of symptoms of depression. Chronic, severe neurogenic pain. Dermatologic disorders including chronic urticaria, angioedema, and nocturnal pruritus in atopic eczema.
Contraindications:
Use in children (safety and efficacy have not been determined).
Laboratory Test Alterations:
Urinary 5-HIAA.
How Supplied:
Capsule: 10 mg, 25 mg, 50 mg, 75 mg;
Solution: 10 mg base/5 mL
Dosage
?Capsules, Oral Solution
Depression.
Adults: 25 mg t.i.d.-q.i.d. Dose individualized; begin at a low dosage and increase as needed.
Doses above 150 mg/day are not recommended. Adolescent and elderly clients: 30-50 mg/day in divided doses or total daily dose may be given once/day.
Dermatologic disorders.
75 mg/day. |