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Hydrochlorothiazide Questions
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Hydrochlorothiazide
Hydrochlorothiazide (Ezide, Hydro-DIURIL)
Hydrochlorothiazide
(
hy-droh-klor-oh-
THIGH-ah-zyd)
Pregnancy Category: B
Apo-Hydro
Esidrex
Ezide
Hydro-Diuril
Hydro-Par
Microzide
Novo-Hydrazide
Oretic
Urozide
(Rx)
Classification:
Diuretic, thiazide type
See Also:
See also
Diuretics, Thiazide
[.
]
Action/Kinetics:
Onset: 2 hr.
Peak effect: 4-6 hr.
Duration: 6-12 hr.
t
1/2: 5.6-14.8 hr.
Additional Uses:
Microzide is available for once-daily, low-dose treatment for hypertension.
Special Concerns:
Geriatric clients may be more sensitive to the usual adult dose.
Additional Side Effects:
CV: Allergic myocarditis, hypotension.
Dermatologic: Alopecia, exfoliative dermatitis,
toxic epidermal necrolysis erythema multiforme,
Stevens-Johnson syndrome.
Miscellaneous:
Anaphylactic reactions, respiratory distress including pneumonitis and pulmonary edema.
How Supplied:
Capsule: 12.5 mg;
Solution: 50 mg/5 mL;
Tablet: 25 mg, 50 mg, 100 mg
Dosage
?Oral Solution, Tablets
Diuretic.
Adults, initial: 25-200 mg/day for several days until dry weight is reached;
then, 25-100 mg/day or intermittently. Some clients may require up to 200 mg/day.
Antihypertensive.
Adults, initial: 25 mg/day as a single dose. The dose may be increased to 50 mg/day in one to two doses. Doses greater than 50 mg may cause significant reductions in serum potassium.
Pediatric, under 6 months: 3.3 mg/kg/day in two doses;
up to 2 years of age: 12.5-37.5 mg/day in two doses;
2-12 years of age: 37.5-100 mg/day in two doses. |
