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Chlorpheniramine maleate Questions
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Chlorpheniramine maleate
Chlorpheniramine maleate (Chlor-Trimeton)
Chlorpheniramine maleate
(klor-fen-
EAR-ah-meen)
Pregnancy Category: B
Syrup
Tablets
Chewable Tablets: Aller-Chlor
Allergy
Chlo-Amine
Chlor-Trimeton Allergy 4 Hour
Chlor-Tripolon
(OTC)
Extended-release Tablets: Chlor-Trimeton 8 Hour and 12 Hour
(OTC)
Injectable: Chlorpheniramine maleate
(Rx)
Classification:
Antihistamine, alkylamine type
See Also:
See also
Antihistamines
[.
]
Action/Kinetics:
Moderate anticholinergic and low sedative activity.
Onset: 15-30 min
t
1/2: 21-27 hr.
Time to peak effect: 6 hr.
Duration: 3-6hr.
Uses:
PO: Allergic rhinitis.
IM, SC: Allergic reactions to blood and plasma and adjunct to anaphylaxis therapy.
Contraindications:
IV or intradermal use. Parenteral route for neonates. Use for children under 6 years of age.
Special Concerns:
Geriatric clients may be more sensitive to the adult dose.
How Supplied:
Capsule, Extended Release: 8 mg, 12 mg;
Injection: 10 mg/mL;
Syrup: 2 mg/5 mL;
Tablet: 4 mg;
Tablet, Extended Release: 8 mg, 12 mg, 16 mg
Dosage
?Syrup, Tablets, Chewable Tablets
Adults
and children over 12 years: 4 mg q 6 hr, not to exceed 24 mg in 24 hr.
Pediatric, 6-12 years: 2 mg (break 4-mg tablets in half) q 4-6 hr, not to exceed 12 mg in 24 hr.
2-6 years: 1 mg (
1/4 of a 4-mg tablet) q 4
-6 hr.
?Extended-Release Tablets
Adults and children over 12 years: 8 mg q 8-12 hr or 12 mg q 12 hr, not to exceed 24 mg in 24 hr.
?IM, SC
Adults and children over 12 years: 5-40 mg for uncomplicated allergic reactions; 10-20 mg for amelioration of allergic reactions to blood or plasma or to treat anaphylaxis. Maximum dose per 24 hr: 40 mg. |
